KLF14 antibody (Kruppel-Like Factor 14) (AA 254-283)

Details for Product anti-KLF14 Antibody No. ABIN654237, Supplier: Log in to see
Antigen
  • BTEB5
  • 5330411L03Rik
  • AL022736
  • Kruppel-like factor 14
  • KLF14
  • Klf14
  • LOC100345494
Epitope
AA 254-283, C-Term
8
7
7
4
Reactivity
Human, Mouse (Murine)
23
8
3
2
1
1
Host
Rabbit
23
Clonality (Clone)
Polyclonal ()
Conjugate
This KLF14 antibody is un-conjugated
2
2
2
2
2
2
Application
Flow Cytometry (FACS), Western Blotting (WB)
20
15
14
2
1
1
1
Options
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Immunogen This KLF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 254-283 AA from the C-terminal region of human KLF14.
Clone RB27698
Isotype Ig
Specificity This KLF14 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 261-291 amino acids from the C-terminal region of human KLF14.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name KLF14 (KLF14 Antibody Abstract)
Background This gene encodes a member of the Kruppel-like family of transcription factors. The gene exhibits imprinted expression from the maternal allele in embryonic and extra-embryonic tissues. Expression of this gene is induced by TGF-beta, and the protein represses TGF-beta receptor II expression. The protein functions as part of a transcriptional co-repressor complex that also contains the transcriptional regulator SIN3A and histone deacetylase 2.
Synonyms: Krueppel-like factor 14,KLF14,BTEB5
Molecular Weight 33124 DA
Gene ID 136259
NCBI Accession NP_619638
UniProt Q8TD94
Research Area Phospho-specific antibodies, Protein Modifications, Transcription Factors, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-KLF14 antibody (Kruppel-Like Factor 14) (AA 254-283) (ABIN654237) KLF14 Antibody (C-term) (ABIN654237) western blot analysis in mouse kidney tissue lys...
Background publications Voight, Scott, Steinthorsdottir, Morris, Dina, Welch, Zeggini, Huth, Aulchenko, Thorleifsson, McCulloch, Ferreira, Grallert, Amin, Wu, Willer, Raychaudhuri, McCarroll, Langenberg, Hofmann, Dupuis, Qi, Segrè, van Hoek, Navarro, Ardlie, Balkau, Benediktsson: "Twelve type 2 diabetes susceptibility loci identified through large-scale association analysis." in: Nature genetics, Vol. 42, Issue 7, pp. 579-89, 2010 (PubMed).

Truty, Lomberk, Fernandez-Zapico, Urrutia: "Silencing of the transforming growth factor-beta (TGFbeta) receptor II by Kruppel-like factor 14 underscores the importance of a negative feedback mechanism in TGFbeta signaling." in: The Journal of biological chemistry, Vol. 284, Issue 10, pp. 6291-300, 2009 (PubMed).

Chasman, Paré, Mora, Hopewell, Peloso, Clarke, Cupples, Hamsten, Kathiresan, Mälarstig, Ordovas, Ripatti, Parker, Miletich, Ridker: "Forty-three loci associated with plasma lipoprotein size, concentration, and cholesterol content in genome-wide analysis." in: PLoS genetics, Vol. 5, Issue 11, pp. e1000730, 2009 (PubMed).

Stacey, Sulem, Masson, Gudjonsson, Thorleifsson, Jakobsdottir, Sigurdsson, Gudbjartsson, Sigurgeirsson, Benediktsdottir, Thorisdottir, Ragnarsson, Scherer, Hemminki, Rudnai, Gurzau, Koppova, Botella-Estrada, Soriano, Juberias, Saez, Gilaberte, Fuentelsaz,: "New common variants affecting susceptibility to basal cell carcinoma." in: Nature genetics, Vol. 41, Issue 8, pp. 909-14, 2009 (PubMed).