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S6A12 (AA 9-38), (N-Term) antibody

Details for Product No. ABIN654460, Supplier: Log in to see
Antigen
Epitope
AA 9-38, N-Term
9
7
1
Reactivity
Human
9
Host
Rabbit
9
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Western Blotting (WB)
8
7
7
Supplier
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Immunogen This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 9-38 AA from the N-terminal region of human S6A12.
Clone RB24381
Isotype Ig
Specificity This S6A12 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-46 amino acids from the N-terminal region of human S6A12.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Background Transports betaine and GABA. May have a role in regulation of GABAergic transmission in the brain through the reuptake of GABA into presynaptic terminals, as well as in osmotic regulation.
Synonyms: SLC6A12,Sodium- and chloride-dependent betaine transporter,
Molecular Weight 69368 DA
Gene ID 6539
NCBI Accession NP_001116319, NP_003035, NP_001116320
UniProt P48065
Research Area Cell Structure, Protein Modifications, Neurology
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-S6A12 (AA 9-38), (N-Term) antibody (ABIN654460) S6A12 Antibody (N-term) western blot analysis in MDA-MB231 cell line lysates (35ug/l...
Flow Cytometry (FACS) image for anti-S6A12 (AA 9-38), (N-Term) antibody (ABIN654460) S6A12 Antibody (N-term) flow cytometric analysis of MDA-MB231 cells (right histogram...
Background publications Pasaje, Kim, Park, Cheong, Chun, Park, Lee, Kim, Bae, Park, Yoon, Uh, Choi, Kim, Kim, Choi, Cho, Choi, Park, Shin: "Association of SLC6A12 variants with aspirin-intolerant asthma in a Korean population." in: Annals of human genetics, Vol. 74, Issue 4, pp. 326-34, 2010 (PubMed).

Köttgen, Pattaro, Böger, Fuchsberger, Olden, Glazer, Parsa, Gao, Yang, Smith, OConnell, Li, Schmidt, Tanaka, Isaacs, Ketkar, Hwang, Johnson, Dehghan, Teumer, Paré, Atkinson, Zeller, Lohman et al.: "New loci associated with kidney function and chronic kidney disease...." in: Nature genetics, Vol. 42, Issue 5, pp. 376-84, 2010 (PubMed).