Intercellular Adhesion Molecule 2 (ICAM2) (AA 191-218), (Center) antibody

Details for Product No. ABIN655000
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Antigen
Synonyms ICAM2, CD102, Icam-2, Ly-60
Epitope
AA 191-218, Center
(15), (10), (9), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(124), (84), (16)
Host
Rabbit
(67), (64), (60), (2)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(30), (25), (15), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(130), (59), (52), (48), (40), (23), (18), (10), (10), (6), (3), (3), (2), (2), (1), (1), (1)
Pubmed 3 references available
Quantity 400 μL
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Catalog No. ABIN655000
291.50 $
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Immunogen This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 AA from the Central region of human ICAM2.
Clone RB28558
Isotype Ig
Specificity This ICAM2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 191-218 amino acids from the Central region of human ICAM2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name ICAM2
Background The protein encoded by this gene is a member of the intercellular adhesion molecule (ICAM) family. All ICAM proteins are type I transmembrane glycoproteins, contain 2-9 immunoglobulin-like C2-type domains, and bind to the leukocyte adhesion LFA-1 protein. This protein may play a role in lymphocyte recirculation by blocking LFA-1-dependent cell adhesion. It mediates adhesive interactions important for antigen-specific immune response, NK-cell mediated clearance, lymphocyte recirculation, and other cellular interactions important for immune response and surveillance. Several transcript variants encoding the same protein have been found for this gene.
Synonyms: Intercellular adhesion molecule 2,ICAM2,
Molecular Weight 30654 DA
Gene ID 3384
NCBI Accession NP_001093258, NP_001093257, NP_001093256, NP_000864, NP_001093259
UniProt P13598
Research Area Cell Signaling, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.48 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Intercellular Adhesion Molecule 2 (ICAM2) (AA 191-218), (Center) antibody ICAM2 Antibody (Center) (ABIN655000) western blot analysis in HepG2 cell line lysates (35 µg/lane). This demonstrates the ICAM2 antibody detected the ICAM2 protein (arrow).
Background publications Sato, Azuma, Higai et al.: "Altered expression of glycoproteins on the cell surface of Jurkat cells during etoposide-induced apoptosis: shedding and intracellular translocation of glycoproteins." in: Biochimica et biophysica acta, Vol. 1790, Issue 10, pp. 1198-205, 2009 (PubMed).

Rajaraman, Brenner, Neta et al.: "Risk of meningioma and common variation in genes related to innate immunity." in: Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, Vol. 19, Issue 5, pp. 1356-61, 2010 (PubMed).

Han, Lan, Park et al.: "Polymorphisms in innate immunity genes and risk of childhood leukemia." in: Human immunology, Vol. 71, Issue 7, pp. 727-30, 2010 (PubMed).

Validation Images
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