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Adenosylhomocysteinase (AHCY) (N-Term), (AA 79-110) antibody

Details for Product No. ABIN655151
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Antigen
Epitope
N-Term, AA 79-110
(10), (9), (2), (2), (1), (1)
Reactivity
Mouse (Murine)
(44), (21), (17), (13), (13), (13), (12), (1), (1)
Host
Rabbit
(35), (11)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Flow Cytometry (FACS)
(35), (19), (10), (10), (5), (2), (1), (1), (1), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN655151
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Immunogen This AHCY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 79-110 AA from the N-terminal region of human AHCY.
Clone RB14650
Isotype Ig
Specificity This AHCY antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 86-118 amino acids from the N-terminal region of human AHCY.
Predicted Reactivity Cow (Bovine),Pig (Porcine),Monkey
Purification This antibody is prepared by Saturated Ammonium Sulfate (SAS) precipitation followed by dialysis against PBS.
Alternative Name AHCY
Background S-adenosylhomocysteine hydrolase belongs to the adenosylhomocysteinase family. It catalyzes the reversible hydrolysis of S-adenosylhomocysteine (AdoHcy) to adenosine (Ado) and L-homocysteine (Hcy). Thus, it regulates the intracellular S-adenosylhomocysteine (SAH) concentration thought to be important for transmethylation reactions. Deficiency in this protein is one of the different causes of hypermethioninemia. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
Synonyms: AHCY,Adenosylhomocysteinase,SAHH
Molecular Weight 47716 DA
Gene ID 191
UniProt P23526, NP_000678
Research Area Cell Structure, Protein Modifications, Signaling, Metabolism
Application Notes WB = 1:1000, IHC = 1:50-100, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 2 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Adenosylhomocysteinase (AHCY) (N-Term), (AA 79-110) antibody AHCY Antibody (N-term) (ABIN655151) flow cytometric analysis of K562 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Background publications Jugessur, Shi, Gjessing et al.: "Maternal genes and facial clefts in offspring: a comprehensive search for genetic associations in two population-based cleft studies from Scandinavia." in: PLoS ONE, Vol. 5, Issue 7, pp. e11493, 2010 (PubMed).

Validation Images
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