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Details for Product No. ABIN655970

Forkhead Box A2 (FOXA2) (C-Term), (AA 380-407) antibody

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Antigen
Synonyms
HNF3B, TCF3B, Hnf3b, Tcf3b, Hnf-3b, Tcf-3b, HNF3beta, HNF3-beta, HNF-3B, ax, axl, fkd1, ik:tdsubc_2g8, tdsubc_2g8, wu:fe05g04, xx:tdsubc_2g8, HNF-3BETA, HNF-3b, hnf3b, xFD-3, FoxA2a, FoxA2-A, xbeta-1, ... show more
Epitope
»Alternatives C-Term, AA 380-407
Reactivity
»Alternatives Human, Rat (Rattus)
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Conjugate
»Alternatives Un-conjugated
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 3 references available
Catalog no. ABIN655970
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-407 AA from the C-terminal region of human FOXA2.
Clone RB31713
Isotype Ig
Specificity This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human FOXA2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOXA2
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Synonyms: FOXA2,Hepatocyte nuclear factor 3-beta,HNF3B, TCF3B
Molecular Weight 48306 DA
Gene ID 3170
UniProt Q9Y261, NP_068556.2
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Xing, Cohen, Boerwinkle: "A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels." in: American journal of human genetics, Vol. 86, Issue 3, pp. 440-6, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).

Dayoub, Groitl, Dobner et al.: "Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 465-70, 2010 (PubMed).

Alternatives for antigen "Forkhead Box A2 (FOXA2)", type "Antibodies"
Hosts (38), (37), (12)
Reactivities (82), (22), (18), (13), (12), (12), (3), (1), (1)
Applications (77), (50), (26), (22), (18), (10), (5), (3), (2), (1), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (12), (5), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
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