Forkhead Box A2 (FOXA2) (C-Term), (AA 380-407) antibody

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Antigen
Synonyms
HNF3B, TCF3B, Hnf3b, Tcf3b, Hnf-3b, Tcf-3b, HNF3beta, HNF3-beta, HNF-3B, ax, axl, fkd1, ik:tdsubc_2g8, tdsubc_2g8, wu:fe05g04, xx:tdsubc_2g8, HNF-3BETA, HNF-3b, hnf3b, xFD-3, FoxA2a, FoxA2-A, xbeta-1, ... show more
HNF3B, TCF3B, Hnf3b, Tcf3b, Hnf-3b, Tcf-3b, HNF3beta, HNF3-beta, HNF-3B, ax, axl, fkd1, ik:tdsubc_2g8, tdsubc_2g8, wu:fe05g04, xx:tdsubc_2g8, HNF-3BETA, HNF-3b, hnf3b, xFD-3, FoxA2a, FoxA2-A, xbeta-1, hnf3beta, hnf3-beta, tcf3b, FOXA2 show less
Epitope
C-Term, AA 380-407
(12), (12), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human, Rat (Rattus)
(83), (24), (18), (13), (12), (12), (3), (1), (1)
Host
Rabbit
(41), (39), (10)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(80), (47), (27), (22), (17), (10), (8), (5), (2), (2), (1), (1)
Pubmed 3 references available
Catalog no. ABIN655970
Quantity 400 µL
Price
238.50 $   Plus shipping costs $45.00
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Immunogen This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 380-407 AA from the C-terminal region of human FOXA2.
Clone RB31713
Isotype Ig
Specificity This FOXA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 387-415 amino acids from the C-terminal region of human FOXA2.
Predicted Reactivity Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FOXA2
Background This gene encodes a member of the forkhead class of DNA-binding proteins. These hepatocyte nuclear factors are transcriptional activators for liver-specific genes such as albumin and transthyretin, and they also interact with chromatin. Similar family members in mice have roles in the regulation of metabolism and in the differentiation of the pancreas and liver. This gene has been linked to sporadic cases of maturity-onset diabetes of the young. Transcript variants encoding different isoforms have been identified for this gene.
Synonyms: FOXA2,Hepatocyte nuclear factor 3-beta,HNF3B, TCF3B
Molecular Weight 48306 DA
Gene ID 3170
UniProt Q9Y261, NP_068556.2
Research Area Translation Factors, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-Forkhead Box A2 (FOXA2) (C-Term), (AA 380-407) antibody FOXA2 Antibody (C-term) western blot analysis in MCF-7 cell line and rat stomach tissue lysates (35ug/lane).This demonstrates the FOXA2 antibody detected the FOXA2 protein (arrow).
anti-Forkhead Box A2 (FOXA2) (C-Term), (AA 380-407) antibody (2) FOXA2 Antibody (C-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human kidney tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of FOXA2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
anti-Forkhead Box A2 (FOXA2) (C-Term), (AA 380-407) antibody (3) Confocal immunofluorescent analysis of FOXA2 Antibody (C-term) with Hela cell followed by Alexa Fluor 488-conjugated goat anti-rabbit lgG (green). Actin filaments have been labeled with Alexa Fluor 555 phalloidin (red).DAPI was used to stain the cell nuclear (blue).
Background publications Xing, Cohen, Boerwinkle: "A weighted false discovery rate control procedure reveals alleles at FOXA2 that influence fasting glucose levels." in: American journal of human genetics, Vol. 86, Issue 3, pp. 440-6, 2010 (PubMed).

Song, Washington, Crawford: "Loss of FOXA1/2 is essential for the epithelial-to-mesenchymal transition in pancreatic cancer." in: Cancer research, Vol. 70, Issue 5, pp. 2115-25, 2010 (PubMed).

Dayoub, Groitl, Dobner et al.: "Foxa2 (HNF-3beta) regulates expression of hepatotrophic factor ALR in liver cells." in: Biochemical and biophysical research communications, Vol. 395, Issue 4, pp. 465-70, 2010 (PubMed).

Hosts (41), (39), (10)
Reactivities (83), (24), (18), (13), (12), (12), (3), (1), (1)
Applications (80), (47), (27), (22), (17), (10), (8), (5), (2), (2), (1), (1)
Conjugates (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Epitopes (12), (12), (3), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1)
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