RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (N-Term), (AA 7-34) antibody

Details for Product No. ABIN656117
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Antigen
Synonyms RASGRP2, CALDAG-GEFI, CDC25L, CalDAG-GEFI, Caldaggef1
Epitope
N-Term, AA 7-34
(10), (8), (3), (1), (1), (1), (1), (1)
Reactivity
Human
(23), (4), (3), (1), (1)
Host
Rabbit
(18), (5)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
(21), (14), (7), (6), (2), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
Options
Shipping to United States (Change)
Availability Will be delivered in 2 to 3 Business Days
Request Want additional data for this product?

The Independent Validation Initiative strives to provide you with high quality data. Find out more

Catalog No. ABIN656117
291.50 $
Plus shipping costs $45.00

Order hotline:

  • +1 404 474 4654
  • +1 888 205 9894 (TF)
Immunogen This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 AA from the N-terminal region of human RASGRP2.
Clone RB32230
Isotype Ig
Specificity This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RASGRP2.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASGRP2
Background The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms: RASGRP2,RAS guanyl-releasing protein 2,CDC25L, MCG7
Molecular Weight 75kd Isoform 2. 69248 Da
Gene ID 10235
UniProt Q7LDG7
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure, Neurology
Application Notes WB = 1:1000, IHC = 1:10-50, IF = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Supplier Images
anti-RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (N-Term), (AA 7-34) antibody RASGRP2 Antibody (N-term) (ABIN656117) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.
Background publications Eto, Murphy, Kerrigan et al.: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, 2002 (PubMed).

Validation Images
Did you look for something else?
back to top