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Details for Product No. ABIN656117

RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2) (N-Term), (AA 7-34) antibody

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Antigen
Synonyms CDC25L, CALDAG-GEFI, Caldaggef1, CalDAG-GEFI, RASGRP2
Epitope
»Alternatives N-Term, AA 7-34
Reactivity
»Alternatives Human
Host
»Alternatives Rabbit
Clonality (Clone) Polyclonal ()
Application
»Alternatives Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF)
Pubmed 1 reference available
Catalog no. ABIN656117
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 7-34 AA from the N-terminal region of human RASGRP2.
Clone RB32230
Isotype Ig
Specificity This RASGRP2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 14-42 amino acids from the N-terminal region of human RASGRP2.
Predicted Reactivity Cow (Bovine),Mouse (Murine),Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name RASGRP2
Background The protein encoded by this gene is a brain-enriched nucleotide exchanged factor that contains an N-terminal GEF domain, 2 tandem repeats of EF-hand calcium-binding motifs, and a C-terminal diacylglycerol/phorbol ester-binding domain. This protein can activate small GTPases, including RAS and RAP1/RAS3. The nucleotide exchange activity of this protein can be stimulated by calcium and diacylglycerol. Three alternatively spliced transcript variants encoding the same protein have been found for this gene.
Synonyms: RASGRP2,RAS guanyl-releasing protein 2,CDC25L, MCG7
Molecular Weight 75kd Isoform 2. 69248 Da
Gene ID 10235
UniProt Q7LDG7
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure, Neurology
Application Notes Recommend dilutions: WB : 1:1000,IHC : 1:10-50,IF : 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.25 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Maintain refrigerated at 2-8 °C for up to 6 months. For long term storage store at -20 °C in small aliquots to prevent freeze-thaw cycles.
Expiry Date 6 months
Background publications Eto, Murphy, Kerrigan et al.: "Megakaryocytes derived from embryonic stem cells implicate CalDAG-GEFI in integrin signaling." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 99, Issue 20, pp. 12819-24, 2002 (PubMed).

Alternatives for antigen "RAS Guanyl Releasing Protein 2 (Calcium and DAG-Regulated) (RASGRP2)", type "Antibodies"
Hosts (11), (5)
Reactivities (15), (3), (3), (1), (1)
Applications (14), (8), (3), (2), (1)
Epitopes (5), (3), (2), (1)
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