This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This CCT8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 519-548 amino acids from the C-terminal region of human CCT8.
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
CCT8 Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Yin, Miao, Wu, Wei, Zong, Yang, Chen, Zheng, Zhu, Guo, Li, Chen, Wang, He: "The role of the Chaperonin containing t-complex polypeptide 1, subunit 8 (CCT8) in B-cell non-Hodgkin's lymphoma." in: Leukemia research, Vol. 45, pp. 59-67, (2017) (PubMed).
Qiu, He, Huang, Liu, Sun, Guo, Yuan, Yang, Ban, Fan, Tao, Wang: "Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in glioma." in: Pathology, research and practice, Vol. 211, Issue 10, pp. 717-25, (2016) (PubMed).
Molecular chaperone, CCT8 assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin.