APBA2 antibody (AA 307-336)

Catalog No. ABIN656588

Product Details anti-APBA2 Antibody

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Binding Specificity: AA 307-336

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This APBA2 antibody is un-conjugated

Application: Western Blotting (WB)

Predicted Reactivity: Rat

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This APBA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 307-336 amino acids from the Central region of human APBA2.

Clone: RB31057

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: APG10L Antibody (C-term S116) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for APBA2

Target: APBA2 (Amyloid beta (A4) Precursor Protein-Binding, Family A, Member 2 (APBA2))

Alternative Name: APBA2 (APBA2 Products)

Synonyms: MGC83599 antibody, D15S1518E antibody, HsT16821 antibody, LIN-10 antibody, MGC:14091 antibody, MINT2 antibody, X11-BETA antibody, X11L antibody, X11-like antibody, XllL antibody, mXllL antibody, Mint2 antibody, amyloid beta precursor protein binding family A member 2 antibody, amyloid beta (A4) precursor protein-binding, family A, member 2 L homeolog antibody, amyloid beta (A4) precursor protein-binding, family A, member 2 antibody, APBA2 antibody, apba2.L antibody, Apba2 antibody

Background: The protein encoded by this gene is a member of the X11 protein family. It is a neuronal adapter protein that interacts with the Alzheimer's disease amyloid precursor protein (APP). It stabilizes APP and inhibits production of proteolytic APP fragments including the A beta peptide that is deposited in the brains of Alzheimer's disease patients. This gene product is believed to be involved in signal transduction processes. It is also regarded as a putative vesicular trafficking protein in the brain that can form a complex with the potential to couple synaptic vesicle exocytosis to neuronal cell adhesion. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].

Molecular Weight: 82512

Gene ID: 321

NCBI Accession: NP_001123886, NP_005494

UniProt: Q99767

Pathways: Synaptic Vesicle Exocytosis