Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))
Purification
This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This SLC23A1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human SLC23A1.
SVCT1
Reactivity: Human
ELISA, WB, IHC
Host: Rabbit
Polyclonal
PE
Application Notes
WB: 1:1000. WB: 1:1000-1:2000. IHC-P-Leica: 1:500
Restrictions
For Research Use only
Format
Liquid
Buffer
Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.
Preservative
Sodium azide
Precaution of Use
This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C,-20 °C
Storage Comment
SLC23A1 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date
6 months
Subramanian, Nabokina, Patton, Marchant, Moradi, Said: "Glyoxalate reductase/hydroxypyruvate reductase interacts with the sodium-dependent vitamin C transporter-1 to regulate cellular vitamin C homeostasis." in: American journal of physiology. Gastrointestinal and liver physiology, Vol. 304, Issue 12, pp. G1079-86, (2013) (PubMed).
Target
SLC23A1 (SVCT1)
(Sodium Dependent Vitamin C Transporter 1 (SVCT1))
SLC23A2 antibody, SVCT1 antibody, YSPL3 antibody, D18Ucla2 antibody, Slc23a2 antibody, solute carrier family 23 member 1 antibody, solute carrier family 23 (nucleobase transporters), member 1 antibody, SLC23A1 antibody, Slc23a1 antibody
Background
The absorption of vitamin C into the body and its distribution to organs requires two sodium-dependent vitamin C transporters. This gene encodes one of the two transporters. The encoded protein is active in bulk vitamin C transport involving epithelial surfaces. Previously, this gene had an official symbol of SLC23A2. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq].