NDUFAF4 antibody (NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 4) (AA 33-61)

Details for Product anti-NDUFAF4 Antibody No. ABIN656909, Supplier: Log in to see
Antigen
  • C6orf66
  • 1110007M04Rik
  • 3000003G13Rik
  • AW214064
  • C9H6ORF66
  • HRPAP20
  • My013
  • bA22L21.1
  • Hrpap20
  • NADH:ubiquinone oxidoreductase complex assembly factor 4
  • NADH dehydrogenase (ubiquinone) 1 alpha subcomplex, assembly factor 4
  • NDUFAF4
  • Ndufaf4
Epitope
AA 33-61, N-Term
10
9
9
1
1
1
Reactivity
Human
27
3
3
Host
Rabbit
27
Clonality (Clone)
Polyclonal ()
Conjugate
This NDUFAF4 antibody is un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
25
17
16
5
1
1
1
1
Options
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Immunogen This NDUFAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 33-61 AA from the N-terminal region of human NDUFAF4.
Clone RB32512
Isotype Ig
Specificity This NDUFAF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 32-61 amino acids from the N-terminal region of human NDUFAF4.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name NDUFAF4 (NDUFAF4 Antibody Abstract)
Background NADH:ubiquinone oxidoreductase (complex I) catalyzes the transfer of electrons from NADH to ubiquinone (coenzyme Q) in the first step of the mitochondrial respiratory chain, resulting in the translocation of protons across the inner mitochondrial membrane. This gene encodes a complex I assembly factor. Mutations in this gene are a cause of mitochondrial complex I deficiency. [provided by RefSeq].
Synonyms: NADH dehydrogenase [ubiquinone] 1 alpha subcomplex assembly factor 4,NDUFAF4,C6orf66, HRPAP20
Molecular Weight 20266 DA
Gene ID 29078
NCBI Accession NP_054884
UniProt Q9P032
Research Area Phospho-specific antibodies, Protein Modifications, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment NDUFAF4 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Immunohistochemistry (IHC) image for anti-NADH Dehydrogenase (Ubiquinone) 1 alpha Subcomplex, Assembly Factor 4 (NDUFAF4) (AA 33-61), (N-Term) antibody (ABIN656909) NDUFAF4 Antibody (N-term) (ABIN656909) immunohistochemistry analysis in formalin fixe...
Background publications Saada, Vogel, Hoefs, van den Brand, Wessels, Willems, Venselaar, Shaag, Barghuti, Reish, Shohat, Huynen, Smeitink, van den Heuvel, Nijtmans: "Mutations in NDUFAF3 (C3ORF60), encoding an NDUFAF4 (C6ORF66)-interacting complex I assembly protein, cause fatal neonatal mitochondrial disease." in: American journal of human genetics, Vol. 84, Issue 6, pp. 718-27, 2009 (PubMed).

Zimmermann, Mayr, Neureiter, Feichtinger, Alinger, Jones, Eder, Sperl, Kofler: "Lack of complex I is associated with oncocytic thyroid tumours." in: British journal of cancer, Vol. 100, Issue 9, pp. 1434-7, 2009 (PubMed).

Saada, Edvardson, Rapoport, Shaag, Amry, Miller, Lorberboum-Galski, Elpeleg: "C6ORF66 is an assembly factor of mitochondrial complex I." in: American journal of human genetics, Vol. 82, Issue 1, pp. 32-8, 2008 (PubMed).

Tozlu-Kara, Roux, Andrieu, Vendrell, Vacher, Lazar, Spyratos, Tubiana-Hulin, Cohen, Dessen, Lidereau, Bièche: "Oligonucleotide microarray analysis of estrogen receptor alpha-positive postmenopausal breast carcinomas: identification of HRPAP20 and TIMELESS as outstanding candidate markers to predict the response to tamoxifen." in: Journal of molecular endocrinology, Vol. 39, Issue 4, pp. 305-18, 2007 (PubMed).

Karp, Shukla, Buckley, Buckley: "HRPAP20: a novel calmodulin-binding protein that increases breast cancer cell invasion." in: Oncogene, Vol. 26, Issue 12, pp. 1780-8, 2007 (PubMed).

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