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Histone H2B Type 1-N (AA 1-30), (N-Term) antibody

Details for Product No. ABIN657039, Supplier: Log in to see
Antigen
  • Hist1h2bm
  • Hist1h2bn
  • HIST1H2BK
  • H2B/d
  • H2BFD
  • HIST1H2BM
  • HIST1H2BN
Epitope
AA 1-30, N-Term
15
14
1
1
Reactivity
Human
18
1
1
Host
Rabbit
17
1
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
2
2
2
2
2
2
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
16
16
14
1
Supplier
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Immunogen This HIST1H2BN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human HIST1H2BN.
Clone RB32147
Isotype Ig
Specificity This HIST1H2BN antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human HIST1H2BN.
Predicted Reactivity Cow (Bovine),Mouse (Murine)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name HIST1H2BN
Background Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Two molecules of each of the four core histones (H2A, H2B, H3, and H4) form an octamer, around which approximately 146 bp of DNA is wrapped in repeating units, called nucleosomes. The linker histone, H1, interacts with linker DNA between nucleosomes and functions in the compaction of chromatin into higher order structures. This gene is intronless and encodes a member of the histone H2B family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the small histone gene cluster on chromosome 6p22-p21.3.
Synonyms: Histone H2B type 1-N,HIST1H2BN,H2BFD
Research Area Ubiquitin-related antibodies, Signaling, Phospho-specific antibodies, Protein Modifications, Transcription Factors, Chromatin, Cell Structure
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Immunohistochemistry (IHC) image for anti-Histone H2B Type 1-N (AA 1-30), (N-Term) antibody (ABIN657039) HIST1H2BN Antibdy (N-term) (ABIN657039) immunohistochemistry analysis in formalin fix...
Background publications Zhu, Zheng, Pham et al.: "Monoubiquitination of human histone H2B: the factors involved and their roles in HOX gene regulation." in: Molecular cell, Vol. 20, Issue 4, pp. 601-11, 2005 (PubMed).