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Delta(4)-Desaturase, Sphingolipid 1 (DEGS1) (AA 1-30), (N-Term) antibody

Details for Product No. ABIN657334, Supplier: Log in to see
Antigen
  • AA536663
  • DEGS
  • degs
  • Degs
  • DEGS-1
  • Des-1
  • Des1
  • DES1
  • FADS7
  • im:6909319
  • Mdes
  • MLD
  • wu:fa25h01
  • wu:fb81d06
Epitope
AA 1-30, N-Term
17
15
2
2
2
Reactivity
Human
47
22
22
1
1
1
1
Host
Rabbit
41
6
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
3
3
3
2
2
2
1
1
1
1
1
1
1
1
1
Application
Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
30
24
17
11
6
1
Supplier
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Immunogen This DEGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human DEGS1.
Clone RB33441
Isotype Ig
Specificity This DEGS1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human DEGS1.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name DEGS1 (DEGS1 Antibody Abstract)
Background This gene encodes a member of the membrane fatty acid desaturase family which is responsible for inserting double bonds into specific positions in fatty acids. This protein contains three His-containing consensus motifs that are characteristic of a group of membrane fatty acid desaturases. It is predicted to be a multiple membrane-spanning protein localized to the endoplasmic reticulum. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor.
Synonyms: Sphingolipid delta(4)-desaturase DES1,DEGS1,DES1, MLD
Research Area Phospho-specific antibodies, Cell Structure, Protein Modifications, Metabolism
Application Notes WB = 1:1000, IHC (p) = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.45 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Supplier Images
Western Blotting (WB) image for anti-Delta(4)-Desaturase, Sphingolipid 1 (DEGS1) (AA 1-30), (N-Term) antibody (ABIN657334) DEGS1 Antibody (N-term) (ABIN657334) western blot analysis in T47D cell line lysates ...
Background publications Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: "hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes." in: Genomics, Vol. 89, Issue 3, pp. 307-15, 2007