This antibody is purified through a protein A column, followed by peptide affinity purification.
Immunogen
This MORC1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 892-921 amino acids from the C-terminal region of human MORC1.
This gene encodes the human homolog of mouse morc and like the mouse protein it is testis-specific. Mouse studies support a testis-specific function since only male knockout mice are infertile, infertility is the only apparent defect. These studies further support a role for this protein early in spermatogenesis, possibly by affecting entry into apoptosis because testis from knockout mice show greatly increased numbers of apoptotic cells.