Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term), (AA 256-285) antibody

Details for Product No. ABIN657646
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Antigen
Synonyms CD32, CD32A, CDw32, FCG2, FCGR2, FCGR2A1, FcGR, IGFR2, CD32a
Epitope
C-Term, AA 256-285
(26), (11), (10), (7), (6), (4), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(105), (10), (6), (6), (1), (1)
Host
Rabbit
(64), (50), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (6), (4), (3), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(72), (55), (35), (17), (15), (14), (13), (10), (5), (2), (1), (1), (1), (1)
Pubmed 2 references available
Quantity 400 µL
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Catalog No. ABIN657646
291.50 $
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Immunogen This FCGR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 256-285 AA from the C-terminal region of human FCGR2A.
Clone RB33694
Isotype Ig
Specificity This FCGR2A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 255-285 amino acids from the C-terminal region of human FCGR2A.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name FCGR2A
Background This gene encodes one member of a family of immunoglobulin Fc receptor genes found on the surface of many immune response cells. The protein encoded by this gene is a cell surface receptor found on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. Alternative splicing results in multiple transcript variants.
Synonyms: Low affinity immunoglobulin gamma Fc region receptor II-a,FCGR2A,CD32, FCG2, FCGR2A1, IGFR2
Molecular Weight 35001 DA
Gene ID 2212
NCBI Accession NP_001129691, NP_067674
UniProt P12318
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.28 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment FCGR2A Antibody (C-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term), (AA 256-285) antibody FCGR2A Antibody (C-term) western blot analysis in NCI-H292 cell line lysates (35ug/lane).This demonstrates the FCGR2A antibody detected the FCGR2A protein (arrow).
anti-Fc Fragment of IgG, Low Affinity IIa, Receptor (CD32) (FCGR2A) (C-Term), (AA 256-285) antibody (2) Western blot analysis of FCGR2A (arrow) using rabbit polyclonal FCGR2A Antibody (C-term) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the FCGR2A gene.
Background publications Dornan, Spleiss, Yeh et al.: "Effect of FCGR2A and FCGR3A variants on CLL outcome." in: Blood, Vol. 116, Issue 20, pp. 4212-22, 2010 (PubMed).

Zhang, Booth: "Divergent intracellular sorting of Fc{gamma}RIIA and Fc{gamma}RIIB2." in: The Journal of biological chemistry, Vol. 285, Issue 44, pp. 34250-8, 2010 (PubMed).

Validation Images
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