Chemokine (C-C Motif) Receptor 10 (CCR10) (N-Term), (AA 1-30) antibody

Details for Product No. ABIN657666
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Antigen
Synonyms zgc:91924, CCR10, AI464239, CCR9, Ccbp2, Cmkbr9, D6, GPR2, Gpr2
Epitope
N-Term, AA 1-30
(10), (8), (6), (4), (3), (3), (1), (1), (1), (1)
Reactivity
Human
(56), (26), (18), (17), (17), (17)
Host
Rabbit
(52), (8), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB)
(31), (27), (26), (18), (10), (3), (3), (2), (1)
Pubmed 1 reference available
Quantity 400 µL
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Catalog No. ABIN657666
291.50 $
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Immunogen This CCR10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 AA from the N-terminal region of human CCR10.
Clone RB33732
Isotype Ig
Specificity This CCR10 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1-30 amino acids from the N-terminal region of human CCR10.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name CCR10
Background Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC, based on the arrangement of the first 2 of the 4 conserved cysteine residues, the 2 cysteines are separated by a single amino acid in CXC chemokines and are adjacent in CC chemokines. CCR10 is the receptor for CCL27 (SCYA27, MIM 604833), CCR10-CCL27 interactions are involved in T cell-mediated skin inflammation (Homey et al., 2002 [PubMed 11821900]).
Synonyms: C-C chemokine receptor type 10,CCR10,GPR2
Molecular Weight 38416 DA
Gene ID 2826
NCBI Accession NP_057686
UniProt P46092
Research Area Phospho-specific antibodies, Cell Signaling, Cell Structure, Protein Modifications
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.4 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment CCR10 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Chemokine (C-C Motif) Receptor 10 (CCR10) (N-Term), (AA 1-30) antibody CCR10 Antibody (N-term) (ABIN657666) western blot analysis in HL-60 cell line lysates (35 µg/lane). This demonstrates the CCR10 antibody detected the CCR10 protein (arrow).
Background publications Davila, Froeling, Tan et al.: "New genetic associations detected in a host response study to hepatitis B vaccine." in: Genes and immunity, Vol. 11, Issue 3, pp. 232-8, 2010 (PubMed).

Validation Images
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