Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2) (N-Term), (AA 16-43) antibody

Details for Product No. ABIN657745
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Antigen
Epitope
N-Term, AA 16-43
(8), (7), (1), (1), (1), (1), (1)
Reactivity
Human, Mouse (Murine)
(29), (17), (16), (12), (2), (1), (1), (1), (1)
Host
Rabbit
(27), (3)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Flow Cytometry (FACS)
(21), (11), (10), (7), (4), (4), (2), (2)
Pubmed 4 references available
Quantity 400 μL
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Catalog No. ABIN657745
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Immunogen This UBE2E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 16-43 AA from the N-terminal region of human UBE2E2.
Clone RB32993
Isotype Ig
Specificity This UBE2E2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 15-43 amino acids from the N-terminal region of human UBE2E2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name UBE2E2
Background Accepts ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro catalyzes 'Lys-11'-and 'Lys-48'-, as well as 'Lys-63'-linked polyubiquitination.
Synonyms: Ubiquitin-conjugating enzyme E2 E2,UBE2E2,UBCH8
Molecular Weight 22255 DA
Gene ID 7325
NCBI Accession NP_689866
UniProt Q96LR5
Research Area Phospho-specific antibodies, Protein Modifications, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000, FACS = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment UBE2E2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Ubiquitin-Conjugating Enzyme E2E 2 (UBE2E2) (N-Term), (AA 16-43) antibody UBE2E2 Antibody (N-term) (ABIN657745) western blot analysis in mouse Neuro-2a,Jurkat,Ramos cell line lysates (35 µg/lane). This demonstrates the UBE2E2 antibody detected the UBE2E2 protein (arrow).
Background publications Takeuchi, Iwahara, Saeki et al.: "Link between the ubiquitin conjugation system and the ISG15 conjugation system: ISG15 conjugation to the UbcH6 ubiquitin E2 enzyme." in: Journal of biochemistry, Vol. 138, Issue 6, pp. 711-9, 2006 (PubMed).

Dubois, Trynka, Franke et al.: "Multiple common variants for celiac disease influencing immune gene expression...." in: Nature genetics, Vol. 42, Issue 4, pp. 295-302, 2010 (PubMed).

Rose, Behm, Drgon et al.: "Personalized smoking cessation: interactions between nicotine dose, dependence and quit-success genotype score." in: Molecular medicine (Cambridge, Mass.), Vol. 16, Issue 7-8, pp. 247-53, 2010 (PubMed).

Yamauchi, Hara, Maeda et al.: "A genome-wide association study in the Japanese population identifies susceptibility loci for type 2 diabetes at UBE2E2 and C2CD4A-C2CD4B." in: Nature genetics, Vol. 42, Issue 10, pp. 864-8, 2010 (PubMed).

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