Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) (N-Term), (AA 11-39) antibody

Details for Product No. ABIN657766
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Antigen
Synonyms agr2, hag3, hag-3, bcmp11, MGC89004, AG2, GOB-4, HAG-2, PDIA17, XAG-2, Agr2h, Gob-4, mAG-2, wu:fj29g05, zgc:112187
Epitope
N-Term, AA 11-39
(27), (14), (11), (10), (9), (7), (5), (4), (2), (2), (1), (1), (1), (1), (1), (1), (1)
Reactivity
Human
(108), (40), (24), (16), (14), (13), (2), (1), (1), (1)
Host
Rabbit
(90), (21), (7), (1)
Clonality (Clone)
Polyclonal ()
Conjugate
Un-conjugated
(6), (3), (3), (2), (2), (2), (2), (2), (2), (1), (1), (1), (1), (1), (1), (1), (1)
Application
Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC)
(89), (62), (48), (35), (14), (10), (9), (9), (6), (4), (2), (1)
Pubmed 1 reference available
Quantity 400 μL
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Catalog No. ABIN657766
291.50 $
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Immunogen This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 11-39 AA from the N-terminal region of human AGR2.
Clone RB33772
Isotype Ig
Specificity This AGR2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 10-39 amino acids from the N-terminal region of human AGR2.
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name AGR2
Background Required for MUC2 post-transcriptional synthesis and secretion. May play a role in the production of mucus by intestinal cells (By similarity). Proto-oncogene that may play a role in cell migration, cell differentiation and cell growth.
Synonyms: Anterior gradient protein 2 homolog,AGR2,AG2
Molecular Weight 19979 DA
Gene ID 10551
NCBI Accession NP_006399
UniProt O95994
Research Area Cell Signaling, Protein Modifications, Cancer, Cell Structure
Application Notes WB = 1:1000, IF = 1:10-50, IHC = 1:10-50
Restrictions For Research Use only
Format Liquid
Concentration 0.37 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment AGR2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-Anterior Gradient Homolog 2 (Xenopus Laevis) (AGR2) (N-Term), (AA 11-39) antibody AGR2 Antibody (N-term) (ABIN657766) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the AGR2 antibody detected the AGR2 protein (arrow).
Background publications Vanderlaag, Hudak, Bald et al.: "Anterior gradient-2 plays a critical role in breast cancer cell growth and survival by modulating cyclin D1, estrogen receptor-alpha and survivin." in: Breast cancer research : BCR, Vol. 12, Issue 3, pp. R32, 2010 (PubMed).

Validation Images
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