TRF2 antibody (AA 308-337)

Catalog No. ABIN657781

This Rabbit Polyclonal antibody specifically detects TRF2 in WB and IHC (p). It exhibits reactivity toward Human.

Quick Overview for TRF2 antibody (AA 308-337) (ABIN657781)

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This TRF2 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Clone: RB33900

Product Details anti-TRF2 Antibody

Binding Specificity: AA 308-337

Purification: This antibody is purified through a protein A column, followed by peptide affinity purification.

Immunogen: This TERF2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 308-337 amino acids from the Central region of human TERF2.

Isotype: Ig Fraction

Application Details

Application Notes: WB: 1:1000. IHC-P: 1:10~50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: Purified polyclonal antibody supplied in PBS with 0.09 % (W/V) sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: TERF2 Antibody (Center) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.

Expiry Date: 6 months

Target Details for TRF2

Target: TRF2 (TERF2) (Telomeric Repeat Binding Factor 2 (TERF2))

Alternative Name: TERF2

Background: This gene encodes a telomere specific protein, TERF2, which is a component of the telomere nucleoprotein complex. This protein is present at telomeres in metaphase of the cell cycle, is a second negative regulator of telomere length and plays a key role in the protective activity of telomeres. While having similar telomere binding activity and domain organization, TERF2 differs from TERF1 in that its N terminus is basic rather than acidic.

Molecular Weight: 59594

Gene ID: 7014

NCBI Accession: NP_005643

UniProt: Q15554

Pathways: Cell Division Cycle, Telomere Maintenance