MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (N-Term), (AA 36-64) antibody

Details for Product No. ABIN657843
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Antigen
Synonyms MNK2, GPRK7, 2010016G11Rik, Gprk7, Mnk2, mknk2, wu:fb37e05, wz5090, gprk7, mnk2
Epitope
N-Term, AA 36-64
(6), (4), (3), (2), (1), (1), (1)
Reactivity
Mouse (Murine)
(23), (7), (7), (2), (1), (1), (1)
Host
Rabbit
(18), (6)
Clonality (Clone)
Polyclonal ()
Application
Western Blotting (WB)
(23), (12), (3), (1), (1), (1), (1)
Pubmed 3 references available
Catalog no. ABIN657843
Quantity 400 µL
Price
291.50 $   Plus shipping costs $45.00
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Immunogen This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 AA from the N-terminal region of mouse Mknk2.
Clone RB34640
Isotype Ig
Specificity This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of human Mouse Mknk2.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Mknk2
Background Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Synonyms: MAP kinase-interacting serine/threonine-protein kinase 2,Mknk2,Mnk2
Molecular Weight 51633 DA
Gene ID 17347
UniProt NP_067437.1, Q8CDB0
Research Area Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Storage 4 °C/-20 °C
Storage Comment Mouse Mknk2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
anti-MAP Kinase Interacting serine/threonine Kinase 2 (MKNK2) (N-Term), (AA 36-64) antibody Mouse Mknk2 Antibody (N-term) (ABIN657843) western blot analysis in mouse lung tissue lysates (35 µg/lane). This demonstrates the Mknk2 antibody detected the Mknk2 protein (arrow).
Background publications Joshi, Kaur, Redig et al.: "Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 29, pp. 12097-102, 2009 (PubMed).

Furic, Rong, Larsson et al.: "eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 14134-9, 2010 (PubMed).

Ueda, Sasaki, Elia et al.: "Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 13984-90, 2010 (PubMed).

Hosts (18), (6)
Reactivities (23), (7), (7), (2), (1), (1), (1)
Applications (23), (12), (3), (1), (1), (1), (1)
Epitopes (6), (4), (3), (2), (1), (1), (1)
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