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MKNK2 antibody (MAP Kinase Interacting serine/threonine Kinase 2) (AA 36-64)

Details for Product anti-MKNK2 Antibody No. ABIN657843, Supplier: Log in to see
Antigen
  • gprk7
  • mnk2
  • GPRK7
  • MNK2
  • 2010016G11Rik
  • Gprk7
  • Mnk2
  • mknk2
  • wu:fb37e05
  • wz5090
Alternatives
anti-Mouse (Murine) MKNK2 antibody for Immunohistochemistry
Epitope
AA 36-64, N-Term
39
21
15
4
4
2
2
2
1
1
1
1
1
Reactivity
Mouse (Murine)
59
23
7
1
1
1
1
Host
Rabbit
67
8
Clonality (Clone)
Polyclonal ()
Conjugate
This MKNK2 antibody is un-conjugated
6
6
6
6
6
6
Application
Western Blotting (WB)
70
53
5
2
1
1
1
Supplier
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Immunogen This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-64 AA from the N-terminal region of mouse Mknk2.
Clone RB34640
Isotype Ig
Specificity This Mouse Mknk2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 35-64 amino acids from the N-terminal region of human Mouse Mknk2.
Predicted Reactivity Rat (Rattus)
Purification This antibody is purified through a protein A column, followed by peptide affinity purification.
Alternative Name Mknk2 (MKNK2 Antibody Abstract)
Background Mknk2 may play a role in the response to environmental stress and cytokines. Appears to regulate transcription by phosphorylating EIF4E, thus increasing the affinity of this protein for the 7-methylguanosine-containing mRNA cap (By similarity).
Synonyms: MAP kinase-interacting serine/threonine-protein kinase 2,Mknk2,Mnk2
Molecular Weight 51633 DA
Gene ID 17347
NCBI Accession NP_067437
UniProt Q8CDB0
Research Area Translation Factors, Phospho-specific antibodies, Cell Signaling, Protein Modifications, Chromatin, Signaling, Cell Structure
Pathways MAPK Signaling
Application Notes WB = 1:1000
Restrictions For Research Use only
Format Liquid
Concentration 0.5 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Mouse Mknk2 Antibody (N-term) can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-MKNK2 antibody (MAP Kinase Interacting serine/threonine Kinase 2) (AA 36-64) (ABIN657843) Mouse Mknk2 Antibody (N-term) (ABIN657843) western blot analysis in mouse lung tissue...
Background publications Ueda, Sasaki, Elia et al.: "Combined deficiency for MAP kinase-interacting kinase 1 and 2 (Mnk1 and Mnk2) delays tumor development." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 13984-90, 2010 (PubMed).

Furic, Rong, Larsson et al.: "eIF4E phosphorylation promotes tumorigenesis and is associated with prostate cancer progression." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 107, Issue 32, pp. 14134-9, 2010 (PubMed).

Joshi, Kaur, Redig et al.: "Type I interferon (IFN)-dependent activation of Mnk1 and its role in the generation of growth inhibitory responses." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 106, Issue 29, pp. 12097-102, 2009 (PubMed).