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ATG4C antibody (ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae))

Details for Product anti-ATG4C Antibody No. ABIN659178, Supplier: Log in to see
Antigen
  • apg4c
  • atg4cl
  • zgc:86888
  • wu:fc56g07
  • APG4-C
  • APG4C
  • AUTL1
  • AUTL3
  • Apg4-C
  • Apg4c
  • Atg4cl
  • Autl1
Reactivity
Mouse (Murine)
104
51
47
3
1
1
Host
Mouse
88
17
9
3
Clonality (Clone)
Monoclonal ()
Conjugate
This ATG4C antibody is un-conjugated
5
3
3
3
2
2
2
1
1
1
1
1
1
1
1
Application
Western Blotting (WB)
92
37
28
15
14
9
3
1
1
Supplier
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Immunogen This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Clone 287CT12-2-2
Isotype IgG1, kappa
Specificity This ATG4C monoclonal antibody is generated from mouse immunized with ATG4C recombinant protein.
Purification This antibody is purified through a protein G column, followed by dialysis against PBS.
Alternative Name ATG4C (ATG4C Antibody Abstract)
Background Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding the same protein, have been characterized. [provided by RefSeq].
Synonyms: ATG4C,Cysteine protease ATG4C,APG4C, AUTL1, AUTL3
Molecular Weight 52497 DA
Gene ID 84938
NCBI Accession NP_835739, NP_116241
UniProt Q96DT6
Research Area Signaling, Protein Modifications, Autophagy, Metabolism, Cell Structure
Application Notes WB = 1:100
Restrictions For Research Use only
Format Liquid
Concentration 0.35 mg/mL
Buffer PBS with 0.09 % (W/V) sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment ATG4C Antibody can be refrigerated at 2-8 °C for up to 6 months. For long term storage, place the at -20 °C.
Expiry Date 6 months
Supplier Images
Western Blotting (WB) image for anti-ATG4C antibody (ATG4 Autophagy Related 4 Homolog C (S. Cerevisiae)) (ABIN659178) ATG4C Antibody western blot analysis in mouse heart tissue lysates (35ug/lane).This ...
Background publications Kathiresan, Melander, Guiducci et al.: "Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans. ..." in: Nature genetics, Vol. 40, Issue 2, pp. 189-97, 2008 (PubMed).

Mariño, Salvador-Montoliu, Fueyo et al.: "Tissue-specific autophagy alterations and increased tumorigenesis in mice deficient in Atg4C/autophagin-3." in: The Journal of biological chemistry, Vol. 282, Issue 25, pp. 18573-83, 2007 (PubMed).