CDKN2C antibody (AA 101-168)

Catalog No. ABIN706181

The Rabbit Polyclonal anti-CDKN2C antibody is suitable to detect CDKN2C in samples from Human. It has been validated for WB, ELISA, IHC (p), IF (cc), IF (p) and IHC (fro).

Quick Overview for CDKN2C antibody (AA 101-168) (ABIN706181)

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN2C antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-CDKN2C Antibody

Binding Specificity: AA 101-168

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDKN2C

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for CDKN2C

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Alternative Name: CDKN2C

Background:

Synonyms: CDK6 inhibitor p18, CDKN 2C, CDKN 6, CDKN2C, CDKN6, CDN2C_HUMAN, Cyclin dependent inhibitor, Cyclin dependent kinase 4 inhibitor C, Cyclin dependent kinase 6 inhibitor, Cyclin dependent kinase 6 inhibitor p18, Cyclin dependent kinase inhibitor 2C p18 inhibits CDK4, Cyclin dependent kinase inhibitor 2C, Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, INK4C, OTTHUMP00000046546, p18, p18 inhibits CDK4, p18 INK4C, p18 INK6, p18-INK4C, p18-INK6.

Background: p18 INK4C is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.

Gene ID: 1031

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases