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CDKN2C antibody

CDKN2C Reactivity: Human, Mouse, Rat IHC, IF Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN7260089
  • Target See all CDKN2C Antibodies
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Reactivity
    • 60
    • 16
    • 10
    • 2
    • 1
    Human, Mouse, Rat
    Host
    • 53
    • 7
    • 1
    Rabbit
    Clonality
    • 53
    • 7
    Polyclonal
    Conjugate
    • 26
    • 5
    • 5
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This CDKN2C antibody is un-conjugated
    Application
    • 48
    • 23
    • 23
    • 13
    • 13
    • 11
    • 6
    • 4
    • 3
    • 1
    Immunohistochemistry (IHC), Immunofluorescence (IF)
    Characteristics
    Polyclonal Antibody
    Purification
    Affinity purification
    Immunogen
    Recombinant fusion protein of human CDKN2C (NP_523240.1).
    Isotype
    IgG
  • Application Notes
    IHC 1:50-1:100 IF 1:50-1:100
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 mg/mL
    Buffer
    PBS with 0.02 % sodium azide, 50 % glycerol, pH 7.3
    Preservative
    Sodium azide
    Precaution of Use
    This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Avoid freeze / thaw cycles.
  • Target
    CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))
    Alternative Name
    CDKN2C (CDKN2C Products)
    Synonyms
    CDKN2C antibody, p18 antibody, ink4c antibody, p18-ink4c antibody, INK4C antibody, p18-INK4C antibody, C77269 antibody, INK4c antibody, INK4d antibody, p18INK4c antibody, cyclin dependent kinase inhibitor 2C antibody, cyclin-dependent kinase inhibitor 2C antibody, cyclin-dependent kinase inhibitor 2C (p18, inhibits CDK4) antibody, CDKN2C antibody, cdkn2c antibody, Cdkn2c antibody
    Background
    The protein encoded by this gene is a member of the INK4 family of cyclin-dependent kinase inhibitors. This protein has been shown to interact with CDK4 or CDK6, and prevent the activation of the CDK kinases, thus function as a cell growth regulator that controls cell cycle G1 progression. Ectopic expression of this gene was shown to suppress the growth of human cells in a manner that appears to correlate with the presence of a wild-type RB1 function. Studies in the knockout mice suggested the roles of this gene in regulating spermatogenesis, as well as in suppressing tumorigenesis. Two alternatively spliced transcript variants of this gene, which encode an identical protein, have been reported.
    Gene ID
    1031
    UniProt
    P42773
    Pathways
    Cell Division Cycle, Mitotic G1-G1/S Phases
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