CDKN2C antibody (AA 101-168) (Cy5)

Catalog No. ABIN706185

The Cy5-conjugated Rabbit Polyclonal anti-CDKN2C antibody (ABIN706185) specifically detects CDKN2C in WB, IF (cc) and IF (p). The antibody is reactive with Human samples.

Quick Overview for CDKN2C antibody (AA 101-168) (Cy5) (ABIN706185)

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This CDKN2C antibody is conjugated to Cy5

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Product Details anti-CDKN2C Antibody (Cy5)

Binding Specificity: AA 101-168

Predicted Reactivity: Human,Mouse,Rat,Dog,Horse

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human CDKN2C

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for CDKN2C

Target: CDKN2C (Cyclin-Dependent Kinase Inhibitor 2C (p18, Inhibits CDK4) (CDKN2C))

Alternative Name: CDKN2C

Background:

Synonyms: CDK6 inhibitor p18, CDKN 2C, CDKN 6, CDKN2C, CDKN6, CDN2C_HUMAN, Cyclin dependent inhibitor, Cyclin dependent kinase 4 inhibitor C, Cyclin dependent kinase 6 inhibitor, Cyclin dependent kinase 6 inhibitor p18, Cyclin dependent kinase inhibitor 2C p18 inhibits CDK4, Cyclin dependent kinase inhibitor 2C, Cyclin-dependent kinase 4 inhibitor C, Cyclin-dependent kinase 6 inhibitor, INK4C, OTTHUMP00000046546, p18, p18 inhibits CDK4, p18 INK4C, p18 INK6, p18-INK4C, p18-INK6.

Background: p18 INK4C is a specific inhibitor of cdk4 / cdk6 (it interacts strongly with CDK6 and weakly with CDK4), and is expressed during G1 to S transition in the eukaryotic cell division cycle. It is maximally induced as cells enter S phase. Highest expression levels are found in skeletal muscle, but it is also found in the pancreas and heart.

Gene ID: 1031

Pathways: Cell Division Cycle, Mitotic G1-G1/S Phases