KCNH2 antibody (AA 1001-1159) (Biotin)

Catalog No. ABIN734845

This Rabbit Polyclonal antibody specifically detects KCNH2 in ELISA. It exhibits reactivity toward Human and Rat.

Quick Overview for KCNH2 antibody (AA 1001-1159) (Biotin) (ABIN734845)

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Reactivity: Human, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This KCNH2 antibody is conjugated to Biotin

Application: ELISA

Product Details anti-KCNH2 Antibody (Biotin)

Binding Specificity: AA 1001-1159

Cross-Reactivity: Human, Rat

Predicted Reactivity: Mouse,Dog,Pig,Horse,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human HERG

Isotype: IgG

Application Details

Application Notes: ELISA 1:500-1000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for KCNH2

Target: KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))

Alternative Name: KCNH2

Background:

Synonyms: ERG1, HERG, LQT2, SQT1, ERG-1, H-ERG, HERG1, Kv11.1, Potassium voltage-gated channel subfamily H member 2, Eag homolog, Ether-a-go-go-related gene potassium channel 1, Eag-related protein 1, Ether-a-go-go-related protein 1, hERG-1, Voltage-gated potassium channel subunit Kv11.1, KCNH2, ERG

Background: Pore-forming (alpha) subunit of voltage-gated inwardly rectifying potassium channel. Channel properties are modulated by cAMP and subunit assembly. Mediates the rapidly activating component of the delayed rectifying potassium current in heart (IKr). Isoforms USO have no channel activity by themself, but modulates channel characteristics by forming heterotetramers with other isoforms which are retained intracellularly and undergo ubiquitin-dependent degradation.

Gene ID: 3757

UniProt: Q12809