KCNH2 antibody (C-Term, Intracellular)
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- Target See all KCNH2 Antibodies
- KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))
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Binding Specificity
- AA 1106-1159, C-Term, Intracellular
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Reactivity
- Human, Rat, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This KCNH2 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (IHC), Immunofluorescence (IF), Immunocytochemistry (ICC), Immunoprecipitation (IP)
- Cross-Reactivity (Details)
- The antibody recognizes the HERG1b splice variant but not splice variants HERG1-3 and HERG-4
- Characteristics
- Anti-KCNH2 (HERG) Antibody is directed against an intracellular epitope of the human KV11.1 channel. Anti-KCNH2 (HERG) Antibody (ABIN7043544, ABIN7044976 and ABIN7044977)) can be used in western blot, immunoprecipitation, immunohistochemical and immunocytochemical applications. It has been designed to recognize KV11.1 from human, rat, and mouse samples.
- Purification
- The serum was depleted of anti-GST antibodies by affinity chromatography on immobilized GST and then the IgG fraction was purified on immobilized antigen.
- Immunogen
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Immunogen: GST fusion protein
Immunogen Sequence: GST fusion protein with the sequence DSLSQVSQFMACEELPPGAPELPQEGPTRRLSLPGQLGALTSQPLHRHGSDPGS, corresponding to amino acid residues 1106-1159 of human KV11.1 (HERG)
- Isotype
- IgG
- Top Product
- Discover our top product KCNH2 Primary Antibody
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- 25 μL, 50 μL or 0.2 mL double distilled water (DDW), depending on the sample size.
- Concentration
- 0.6 mg/mL
- Buffer
- Reconstituted antibody contains phosphate buffered saline (PBS), pH 7.4, 1 % BSA, 0.05 % Sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- RT,4 °C,-20 °C
- Storage Comment
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Storage before reconstitution: The antibody ships as a lyophilized powder at room temperature. Upon arrival, it should be stored at -20°C.
Storage after reconstitution: The reconstituted solution can be stored at 4°C for up to 1 week. For longer periods, small aliquots should be stored at -20°C. Avoid multiple freezing and thawing. Centrifuge all antibody preparations before use (10000 x g 5 min).
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- Target
- KCNH2 (Potassium Voltage-Gated Channel, Subfamily H (Eag-Related), Member 2 (KCNH2))
- Alternative Name
- KCNH2 (HERG) (KCNH2 Products)
- Synonyms
- ERG1 antibody, HERG antibody, HERG1 antibody, Kv11.1 antibody, LQT2 antibody, SQT1 antibody, erg antibody, KCNH2 antibody, ERG antibody, gp-erg antibody, cerg antibody, derg antibody, erg1 antibody, AI326795 antibody, LQT antibody, Lqt2 antibody, M-erg antibody, Merg1 antibody, merg1a antibody, merg1b antibody, potassium voltage-gated channel subfamily H member 2 antibody, potassium voltage-gated channel, subfamily H (eag-related), member 6a antibody, potassium voltage-gated channel, subfamily H (eag-related), member 2 antibody, potassium voltage-gated channel subfamily H member 6 antibody, KCNH2 antibody, kcnh6a antibody, Kcnh2 antibody, KCNH6 antibody
- Background
- Alternative names: KCNH2 (HERG), KV11.1, Potassium voltage-gated channel subfamily H member 2, Ether-a-go-go-related channel 1
- Gene ID
- 3757
- NCBI Accession
- NM_000238
- UniProt
- Q12809
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