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BPV-1 antibody

Details for Product No. ABIN781761, Supplier: Log in to see
Antigen
Reactivity
Cow (Bovine)
7
Host
Mouse
7
Clonality (Clone)
Monoclonal ()
Application
Immunofluorescence (IF), Immunoprecipitation (IP), Western Blotting (WB)
7
4
3
2
1
Supplier
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Immunogen Recombinant full length BPV type 1 E2 protein purified from E. coli
Clone 5-00E-011
Isotype IgG1
Purification Affinity Chromatography on Protein A
Background The bovine papilloma virus E2 protein is the master regulator of papillomavirus replication and transcription. Binds to the E2RE response element (5'-ACCNNNNNNGGT-3') present in multiple copies in the regulatory region. Can either activate or repress transcription depending on E2RE's position with regards to proximal promoter elements. Repression occurs by sterically hindering the assembly of the transcription initiation complex. The E1-E2 complex binds to the origin of DNA replication.Synonyms: BPV1, Bovine Papilloma Virus Protein E2
Gene ID 10559
UniProt P03122
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Concentration 1.0 mg/mL
Buffer PBS with 50 % Glycerol
Handling Advice Avoid repeated freezing and thawing.
Storage -20 °C
Storage Comment Upon receipt, store (in aliquots) at -20 °C to -70 °C.
Supplier Images
Western Blotting (WB) image for anti-BPV-1 antibody (ABIN781761) anti-BPV-1 antibody
Background publications Koljak, Järving, Kurg, Boeglin, Varvas, Valmsen, Ustav, Brash, Samel: "The basis of prostaglandin synthesis in coral: molecular cloning and expression of a cyclooxygenase from the Arctic soft coral Gersemia fruticosa." in: The Journal of biological chemistry, Vol. 276, Issue 10, pp. 7033-40, 2001 (PubMed).