Insulin antibody (C-Term)
Quick Overview for Insulin antibody (C-Term) (ABIN782191)
Target
See all Insulin (INS) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Binding Specificity
- C-Term
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Specificity
- This antibody reacts to Insulin C-terminal. Reacts with c-terminal pentapeptide of insulin beta-chain. Cross-reacts with human proinsulin, bovine insulin (30 %) and porcine insulin.Aff. Const.:1 x 10e9Me-1
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Cross-Reactivity (Details)
- Also reacts to: Proinsulin, C-term
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Purification
- Affinity chromatography on Protein A
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Purity
- > 90 % pure SDS-PAGE
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Immunogen
- Purified human insulin
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Isotype
- IgG1
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Application Notes
- Optimal working dilution should be determined by the investigator.
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Restrictions
- For Research Use only
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Concentration
- 10,0 mg/mL (OD280nm, E0.1% = 1.4)
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Buffer
- PBS, pH 7.4 containing 0.09 % Sodium azide as preservative
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Preservative
- Sodium azide
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Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store the antibody undiluted at 2-8 °C.
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- Insulin (INS)
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Alternative Name
- Insulin
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Background
- Synonyms: INS
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Gene ID
- 3630
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NCBI Accession
- NP_000198
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UniProt
- P01308
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Pathways
- NF-kappaB Signaling, RTK Signaling, Positive Regulation of Peptide Hormone Secretion, Peptide Hormone Metabolism, Hormone Activity, Carbohydrate Homeostasis, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, Feeding Behaviour, Autophagy, Negative Regulation of intrinsic apoptotic Signaling, Brown Fat Cell Differentiation, Positive Regulation of fat Cell Differentiation
Target
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