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ZC3HAV1 antibody (C-Term)
ZC3HAV1
Reactivity: Human
WB, IF, EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-ZC3HAV1 Antibody
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Target
See all ZC3HAV1 Antibodies
ZC3HAV1
(Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))
Binding Specificity
All epitopes for ZC3HAV1 antibodies
C-Term
Reactivity
All reactivities for ZC3HAV1 antibodies
Human
Host
All hosts for ZC3HAV1 antibodies
Rabbit
Clonality
All clonalities for ZC3HAV1 antibodies
Polyclonal
Conjugate
All conjugates for ZC3HAV1 antibodies
This ZC3HAV1 antibody is un-conjugated
Application
All applications for ZC3HAV1 antibodies
Western Blotting (WB), Immunofluorescence (IF), Enzyme Immunoassay (EIA)
Cross-Reactivity (Details)
Species reactivity (tested):Human
Purification
Affinity chromatography purified via peptide column
Immunogen
14 amino acid peptide near the carboxy terminus of human ZC3HAV1
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Discover our top product ZC3HAV1 Primary Antibody
Alternatives
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS containing 0.02 % sodium azide
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice
Avoid repeated freezing and thawing.
Storage
-20 °C
Storage Comment
Store the antibody (in aliquots) at -20 °C.
Target Details for ZC3HAV1
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Target
ZC3HAV1
(Zinc Finger CCCH-Type, Antiviral 1 (ZC3HAV1))
Alternative Name
ZC3HAV1 (ZC3HAV1 Products )
Synonyms
1200014N16Rik antibody, 2900058M19Rik antibody, 9130009D18Rik antibody, 9830115L13Rik antibody, ARTD13 antibody, D6Bwg1452e antibody, ZAP antibody, Zap antibody, FLB6421 antibody, PARP13 antibody, ZC3H2 antibody, ZC3HDC2 antibody, zinc finger CCCH type, antiviral 1 antibody, zinc finger CCCH-type containing, antiviral 1 antibody, Zc3hav1 antibody, ZC3HAV1 antibody
Background
The zinc finger antiviral protein (ZC3HAV1) is a CCCH type zinc finger protein that induces an innate immunity to infections by retrovirus by preventing the accumulation of viral RNAs in the cytoplasm and recruits the RNA processing exosome to degrade target RNAs, thereby inhibiting virus replication. ZC3HAV1 is localized in the cytoplasm at steady state, but shuttles between nucleus and cytoplasm in a XPO1-dependent manner. ZAP is a direct target gene of IRF3 action in cellular antiviral responses.Synonyms: PRO1677, ZC3HDC2, Zinc finger CCCH domain-containing protein 2, Zinc finger CCCH-type antiviral protein 1, Zinc finger antiviral protein
Gene ID
56829
NCBI Accession
NP_064504
UniProt
Q7Z2W4
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