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NLRP6 antibody (N-Term)

NLRP6 Reactivity: Human WB, EIA Host: Rabbit Polyclonal unconjugated
Catalog No. ABIN783709
  • Target See all NLRP6 Antibodies
    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
    Binding Specificity
    • 15
    • 9
    • 9
    • 8
    • 7
    • 6
    • 6
    • 5
    • 4
    • 2
    • 1
    • 1
    N-Term
    Reactivity
    • 33
    • 31
    • 18
    Human
    Host
    • 60
    • 1
    Rabbit
    Clonality
    • 61
    • 1
    Polyclonal
    Conjugate
    • 19
    • 6
    • 6
    • 6
    • 4
    • 4
    • 2
    • 2
    • 2
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    This NLRP6 antibody is un-conjugated
    Application
    • 36
    • 34
    • 13
    • 13
    • 4
    • 3
    • 3
    • 2
    • 2
    • 2
    Western Blotting (WB), Enzyme Immunoassay (EIA)
    Specificity
    This antibody detects NLRP6 at N-term.
    Cross-Reactivity (Details)
    Species reactivity (tested):Human
    Purification
    Affinity chromatography purified via peptide column
    Immunogen
    16 amino acid peptide near the amino terminus of human NALP6
    Top Product
    Discover our top product NLRP6 Primary Antibody
  • Application Notes
    Optimal working dilution should be determined by the investigator.
    Restrictions
    For Research Use only
  • Buffer
    PBS containing 0.02 % sodium azide
    Preservative
    Sodium azide
    Precaution of Use
    This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
    Handling Advice
    Avoid repeated freezing and thawing.
    Storage
    4 °C/-20 °C
    Storage Comment
    Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
  • Target
    NLRP6 (NLR Family, Pyrin Domain Containing 6 (NLRP6))
    Alternative Name
    NLRP6 (NLRP6 Products)
    Synonyms
    NLRP6 antibody, NALP6 antibody, AVR antibody, CLR11.4 antibody, NAVR antibody, NAVR/AVR antibody, PAN3 antibody, PYPAF5 antibody, AI504961 antibody, Avr antibody, Nalp6 antibody, Navr antibody, Navr/Avr antibody, Pypaf5 antibody, NLR family pyrin domain containing 6 antibody, NLR family, pyrin domain containing 6 antibody, NLRP6 antibody, Nlrp6 antibody
    Background
    NALP proteins include the apoptosis regulator APAF1 (apoptotic protease activating factor 1) and mammalian NOD-LRR proteins and are thought to be involved in inflammation and reproduction. NALP6, also known as PYPAF5, is highly expressed in granulocytes and T cells and co-localizes with the PYRIN-CARD protein ASC. Co-expression of NALP6 with ASC results in a synergistic activation of NF-kB and activated caspase-1-dependent cytokine processing, suggesting that NALP6 functions in immune cells to coordinate the transduction of pro-inflammatory signals.Synonyms: LRR and PYD domains-containing protein 6, NACHT, NALP6, PYPAF5
    Gene ID
    171389
    NCBI Accession
    NP_612202
    UniProt
    P59044
    Pathways
    Inflammasome
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