NLRP13 antibody (N-Term)

Catalog No. ABIN783721

Product Details anti-NLRP13 Antibody

Target: NLRP13 (NLR Family, Pyrin Domain Containing 13 (NLRP13))

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NLRP13 antibody is un-conjugated

Application: Western Blotting (WB), Enzyme Immunoassay (EIA)

Specificity: This antibody detects NLRP13 at N-term.

Cross-Reactivity (Details): Species reactivity (tested):Human

Purification: Affinity chromatography purified via peptide column

Immunogen: 19 amino acid peptide near the amino terminus of human NALP13

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS containing 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freezing and thawing.

Storage: 4 °C/-20 °C

Storage Comment: Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.

Target Details for NLRP13

Target: NLRP13 (NLR Family, Pyrin Domain Containing 13 (NLRP13))

Alternative Name: NLRP13 (NLRP13 Products)

Synonyms: CLR19.7 antibody, NALP13 antibody, NOD14 antibody, PAN13 antibody, NLR family pyrin domain containing 13 antibody, NLRP13 antibody

Background: NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP13 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP13, it has been suggested that it may be implicated in the activation of proinflammatory caspases via inflammasomes.Synonyms: LRR and PYD domains-containing protein 13, NACHT, NALP13, NOD14

Gene ID: 126204

NCBI Accession: NP_789780

UniProt: Q86W25

Pathways: Inflammasome