NLR Family, Pyrin Domain Containing 14 (NLRP14) (N-Term) antibody

Details for Product No. ABIN783723
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Synonyms GC-LRR, Nalp14, Nalp14l, Nalp-iota, 4921520L01Rik, CLR11.2, NALP14, NOD5, PAN8
Human, Mouse (Murine), Rat (Rattus)
(10), (8), (8)
(9), (1)
ELISA, Western Blotting (WB)
(10), (9), (3), (1)
Pubmed 2 references available
Catalog no. ABIN783723
Quantity 0.1 mg
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Immunogen 16 amino acid peptide near the amino terminus of human NALP14
Specificity This antibody detects NALP14 at N-term. Species Reactivity: Tested: Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name NLRP14
Background NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N- terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.
Alternate names: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5
Gene ID 338323
NCBI Accession NP_789792
UniProt Q86W24
Restrictions For Research Use only
Format Liquid
Buffer PBS containing 0.02% sodium azide
Preservative Sodium azide
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Expiry Date 12 months
Background publications Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Tian, Pascal, Monget: "Evolution and functional divergence of NLRP genes in mammalian reproductive systems." in: BMC evolutionary biology, Vol. 9, pp. 202, 2009 (PubMed).

Hosts (9), (1)
Reactivities (10), (8), (8)
Applications (10), (9), (3), (1)
Epitopes (8)
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