NLR Family, Pyrin Domain Containing 14 (NLRP14) (N-Term) antibody

Details for Product No. ABIN783723
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Synonyms NALP14, CLR11.2, GC-LRR, NOD5, PAN8, 4921520L01Rik, Nalp-iota, Nalp14, Nalp14l
Human, Mouse (Murine), Rat (Rattus)
(11), (7), (7)
Enzyme Immunoassay (EIA), Western Blotting (WB)
(11), (10), (3), (2), (1), (1)
Pubmed 2 references available
Quantity 0.1 mg
Shipping to United States ( )
Availability Will be delivered in 6 to 8 Business Days
Immunogen 16 amino acid peptide near the amino terminus of human NALP14
Specificity This antibody detects NALP14 at N-term.
Cross-Reactivity (Details) Species reactivity (tested):Human, mouse, rat
Purification Affinity chromatography purified via peptide column
Alternative Name NLRP14 (NLRP14 Antibody Abstract)
Background NALP proteins are cytoplasmic proteins that form a subfamily within the larger CATERPILLER family and are thought to play a crucial role in cell proliferation and reproduction. Like all other NALP family members, NALP14 has a C-terminal leucine-rich repeat (LRR) region, an N-terminal Pyrin domain (PYD) followed by a NACHT domain, and a NACHT-associated domain. While little is known about the function of NALP14, it has been suggested that it may play a role in spermatogenesis and that mutations in the NALP14 gene might cause spermatogenic failure.Synonyms: NACHT LRR and PYD domains-containing protein 14, NALP14, NOD5, Nucleotide-binding oligomerization domain protein 5
Gene ID 338323
NCBI Accession NP_789792
UniProt Q86W24
Application Notes Optimal working dilution should be determined by the investigator.
Restrictions For Research Use only
Buffer PBS containing 0.02 % sodium azide
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Handling Advice Avoid repeated freezing and thawing.
Storage 4 °C/-20 °C
Storage Comment Store at 2 - 8 °C for up to three months or (in aliquots) at -20 °C for longer.
Supplier Images
Western Blotting (WB) image for anti-NLR Family, Pyrin Domain Containing 14 (NLRP14) (N-Term) antibody (ABIN783723) Western blot analysis of NALP14 in rat brain tissue lysate with NALP14 antibody at 1 ...
Background publications Tian, Pascal, Monget: "Evolution and functional divergence of NLRP genes in mammalian reproductive systems." in: BMC evolutionary biology, Vol. 9, pp. 202, 2009 (PubMed).

Tschopp, Martinon, Burns: "NALPs: a novel protein family involved in inflammation." in: Nature reviews. Molecular cell biology, Vol. 4, Issue 2, pp. 95-104, 2003 (PubMed).

Catalog No. ABIN783723
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