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UCHL1 antibody (C-Term)
UCHL1
Reactivity: Human, Rat, Mouse
WB, IHC (p), EIA
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-UCHL1 Antibody
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Target
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UCHL1
(Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
Binding Specificity
All epitopes for UCHL1 antibodies
C-Term
Reactivity
All reactivities for UCHL1 antibodies
Human, Rat, Mouse
Host
All hosts for UCHL1 antibodies
Rabbit
Clonality
All clonalities for UCHL1 antibodies
Polyclonal
Conjugate
All conjugates for UCHL1 antibodies
This UCHL1 antibody is un-conjugated
Application
All applications for UCHL1 antibodies
Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Enzyme Immunoassay (EIA)
Specificity
This antibody detects endogenous levels of total PGP9.5 protein.
Cross-Reactivity (Details)
Species reactivity (expected):Mouse and Rat. Species reactivity (tested):Human.
Purification
Immunoaffinity Chromatography
Immunogen
Synthetic peptide - KLH conjugated Remarks: Antigen Modification: C-Terminus
Isotype
IgG
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Discover our top product UCHL1 Primary Antibody
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Application Details
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Application Notes
Optimal working dilution should be determined by the investigator.
Restrictions
For Research Use only
Handling
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Concentration
1.0 mg/mL
Buffer
PBS (without Mg2+, Ca2+), pH 7.4, 150 mM Sodium Chloride, 0.02 % Sodium Azide and 50 % Glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
-20 °C
Storage Comment
Store the antibody (in aliquots) at -20 °C. Avoid freeze-thaw cycles.
Target Details for UCHL1
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Target
UCHL1
(Ubiquitin Carboxyl-terminal Esterase L1 (Ubiquitin Thiolesterase) (UCHL1))
Alternative Name
UCHL1 / PGP9.5 (UCHL1 Products )
Synonyms
PARK5 antibody, PGP 9.5 antibody, PGP9.5 antibody, PGP95 antibody, Uch-L1 antibody, UCH-L1 antibody, UCHL1 antibody, cb358 antibody, wu:fc55h08 antibody, park5 antibody, pgp9.5 antibody, uch-l1 antibody, MGC132191 antibody, uchl1 antibody, AW822034 antibody, C88048 antibody, R75593 antibody, UCHL-1 antibody, gad antibody, ubiquitin C-terminal hydrolase L1 antibody, ubiquitin carboxyl-terminal esterase L1 (ubiquitin thiolesterase) antibody, ubiquitin C-terminal hydrolase L1 L homeolog antibody, ubiquitin carboxyl-terminal esterase L1 antibody, ubiquitin carboxy-terminal hydrolase L1 antibody, UCHL1 antibody, uchl1 antibody, uchl1.L antibody, LOC100304750 antibody, Uchl1 antibody
Background
UCHL1 is a member of family of proteins that hydrolyze small C-terminal adducts of ubiquitin to generate the ubiquitin monomer. The expression of UCHL1 is highly specific to neurons and to cell of the diffuse neuroendocrine system and their tumors. UCHL1 exhibits both and hydrolase and a ligase activity. The S18Y variant of UCHL1, that has reduced ligase activity, has been linked to susceptibility for Parkinson's disease.Synonyms: Neuron cytoplasmic protein 9.5, PGP 9.5, UCH-L1, Ubiquitin carboxyl-terminal hydrolase isozyme L1, Ubiquitin thioesterase L1
Gene ID
7345
NCBI Accession
NP_004172
Pathways
Feeding Behaviour
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