YWHAB antibody (Middle Region)

Catalog No. ABIN784696

Product Details anti-YWHAB Antibody

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Binding Specificity: Middle Region

Reactivity: Human, Mouse, Rat, Cow, Dog, Sheep, Rabbit, Guinea Pig, Horse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This YWHAB antibody is un-conjugated

Application: Western Blotting (WB)

Sequence: KTERNEKKQQ MGKEYREKIE AELQDICNDV LELLDKYLIP NATQPESKVF

Predicted Reactivity: Cow: 87%, Dog: 87%, Guinea Pig: 87%, Horse: 80%, Human: 87%, Mouse: 87%, Rabbit: 87%, Rat: 87%, Sheep: 87%

Characteristics: This is a rabbit polyclonal antibody against YWHAB. It was validated on Western Blot.

Purification: Affinity Purified

Immunogen: The immunogen is a synthetic peptide directed towards the middle region of human YWHAB

Application Details

Application Notes: Optimal working dilutions should be determined experimentally by the investigator.

Comment:

Antigen size: 246 AA

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeated freeze-thaw cycles.

Storage: -20 °C

Storage Comment: For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Target Details for YWHAB

Target: YWHAB (14-3-3 alpha + beta (YWHAB))

Alternative Name: YWHAB (YWHAB Products)

Synonyms: GW128 antibody, HS1 antibody, KCIP-1 antibody, YWHAA antibody, 1300003C17Rik antibody, wu:fb22g04 antibody, wu:fr86a12 antibody, ywhab antibody, ywhab2 antibody, zgc:64092 antibody, 14-3-3beta antibody, fb80c08 antibody, fk41f08 antibody, wu:fb80c08 antibody, wu:fd11d01 antibody, wu:fk41f08 antibody, ywhab1 antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide b antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta S homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein beta L homeolog antibody, tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein, beta polypeptide a antibody, YWHAB antibody, Ywhab antibody, ywhabb antibody, ywhab.S antibody, ywhab.L antibody, ywhaba antibody

Background: YWHAB belongs to the 14-3-3 family, members of which mediate signal transduction by binding to phosphoserine-containing proteins. YWHAB has been shown to interact with RAF1 and CDC25 phosphatases, suggesting that it may play a role in linking mitogenic signaling and the cell cycle machinery.
Alias Symbols: GW128, HS1, KCIP-1, YWHAA
Protein Interaction Partner: ZFP36, UBC, DDIT4, DTL, Crtc2, ABL1, SIK3, SUMO2, IRS4, LDHB, DAK, SMS, SGTA, PGD, PAK2, PAFAH1B2, YWHAQ, TUBB4B, RRAGB, SLC9A3R1, BCCIP, GSS, G6PD, CAPZA1, LRRK2, MARK3, CBL, ZFP36L2, BRAF, BAD, ARAF, AMPD2, PKP2, PI4KB, PIK3C2A, PFKFB2, CDK18, CDK17, CD
Protein Size: 246

Molecular Weight: 28 kDa

Gene ID: 7529

NCBI Accession: NM_003404, NP_003395

UniProt: P31946

Pathways: Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, Myometrial Relaxation and Contraction, Maintenance of Protein Location