H2AFZ antibody (N-Term)
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- Target See all H2AFZ Antibodies
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
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Binding Specificity
- N-Term
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Reactivity
- Human, Mouse, Rat, Cow, Zebrafish (Danio rerio), Sheep, Dog, Guinea Pig, Rabbit, Horse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This H2AFZ antibody is un-conjugated
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Application
- Western Blotting (WB)
- Sequence
- AGGKAGKDSG KAKTKAVSRS QRAGLQFPVG RIHRHLKSRT TSHGRVGATA
- Predicted Reactivity
- Cow: 100%, Dog: 100%, Guinea Pig: 100%, Horse: 93%, Human: 100%, Mouse: 100%, Rabbit: 93%, Rat: 100%, Sheep: 100%, Zebrafish: 100%
- Characteristics
- This is a rabbit polyclonal antibody against H2AFZ. It was validated on Western Blot.
- Purification
- Affinity Purified
- Top Product
- Discover our top product H2AFZ Primary Antibody
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- Application Notes
- Optimal working dilutions should be determined experimentally by the investigator.
- Comment
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Antigen size: 128 AA
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- Lot specific
- Buffer
- Liquid. Purified antibody supplied in 1x PBS buffer with 0.09 % (w/v) sodium azide and 2 % sucrose.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freeze-thaw cycles.
- Storage
- -20 °C
- Storage Comment
- For short term use, store at 2-8°C up to 1 week. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.
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- Target
- H2AFZ (H2A Histone Family, Member Z (H2AFZ))
- Alternative Name
- H2AFZ (H2AFZ Products)
- Synonyms
- H2A.Z-1 antibody, H2A.z antibody, H2A/z antibody, H2AZ antibody, H2A.Z antibody, H2a.z-1 antibody, H2AFV antibody, H2Az antibody, XH2AZ antibody, h2a.zl1 antibody, h2a.zl2 antibody, H2A histone family member Z antibody, H2A histone family, member Z antibody, H2A histone family member Z L homeolog antibody, histone H2A.Z antibody, H2AFZ antibody, H2afz antibody, h2afz.L antibody
- Background
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Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene encodes a replication-independent member of the histone H2A family that is distinct from other members of the family. Studies in mice have shown that this particular histone is required for embryonic development and indicate that lack of functional histone H2A leads to embryonic lethality.
Alias Symbols: H2A.z, H2A/z, H2AZ, MGC117173
Protein Interaction Partner: UBC, ASB9, ASB16, WWOX, ZBTB1, OGFOD1, TRNT1, ACAA2, NOL3, EZR, PYGL, PSMD9, FH, UBD, PAN2, HIST1H3B, CENPA, MAGEC1, SUMO1, SUMO3, NEDD8, EPC1, MEAF6, ACTR6, EP400, DMAP1, MRGBP, ING3, MORF4L1, RUVBL2, SRCAP, KAT5, RUVBL1, TRRAP, YEATS4, VPS72, ACTL6A, HI
Protein Size: 128 - Molecular Weight
- 14 kDa
- Gene ID
- 3015
- NCBI Accession
- NM_002106, NP_002097
- UniProt
- P0C0S5
- Pathways
- Telomere Maintenance
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