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- Target See all PRDM1 Antibodies
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This PRDM1 antibody is un-conjugated
- Application
- Please inquire
- Specificity
- Blimp-1 Antibody, pAb, Rabbit detects endogenous levels of human Blimp-1.
- Cross-Reactivity (Details)
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It is predicted to react with mouse Blimp-1 according to sequence homology.
Reactivity to other species is not tested yet. - Characteristics
- Blimp-1 Antibody, pAb, Rabbit is developed in rabbit using a KLH-coupled synthetic peptide from C-terminal of human Blimp-1 (Swiss Prot: O75626).
- Purification
- Immunoaffinity chromatography
- Immunogen
- KLH-coupled synthetic peptide from C-terminal of human Blimp-1
- Isotype
- IgG
- Top Product
- Discover our top product PRDM1 Primary Antibody
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- Comment
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Positive Control: K562, Ramos
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Reconstitution
- Reconstitute the lyophilized powder with deionized water (or equivalent) to an antibody concentration of 0.5 mg/mL.
- Concentration
- 0.5 mg/mL
- Buffer
- Lyophilized with PBS, pH 7.4, containing 0.02 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Handling Advice
- Avoid repeated freezing and thawing cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- The antibody is stable in lyophilized form if stored at -20°C or below. The reconstituted antibody can be stored for 2-3 weeks at 2-8°C. For long term storage, aliquot and store at -20°C or below.
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." in: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
: "Molecular mechanisms that control the expression and activity of Bcl-6 in TH1 cells to regulate flexibility with a TFH-like gene profile." in: Nature immunology, Vol. 13, Issue 4, pp. 405-11, (2012) (PubMed).
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c-Myc-induced transcription factor AP4 is required for host protection mediated by CD8+ T cells." in: Nature immunology, Vol. 15, Issue 9, pp. 884-93, (2014) (PubMed).
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- Target
- PRDM1 (PR Domain Containing 1, with ZNF Domain (PRDM1))
- Alternative Name
- Blimp-1 (PRDM1 Products)
- Synonyms
- GB11750 antibody, CG5249 antibody, Dmel\\CG5249 antibody, blimp-1 antibody, dBlimp-1 antibody, dBlimp1 antibody, Blimp-1 antibody, Blimp1 antibody, nrd antibody, prdm1 antibody, ubo antibody, wu:fb99c12 antibody, zgc:91885 antibody, MGC52536 antibody, PRDM1 antibody, blimp1 antibody, xblimp1 antibody, prdi-bf1 antibody, BLIMP1 antibody, PRDI-BF1 antibody, ZNFPR1A1 antibody, PR/SET domain 1 antibody, probable serine/threonine-protein kinase DDB_G0282963 antibody, CG5249 gene product from transcript CG5249-RF antibody, blimp-1 antibody, PR domain containing 1a, with ZNF domain antibody, PR domain 1 S homeolog antibody, B lymphocyte induced maturation protein 1 antibody, PR domain 1 antibody, PR domain containing 1, with ZNF domain antibody, PRDM1 antibody, LOC408295 antibody, Blimp-1 antibody, CpipJ_CPIJ007425 antibody, prdm1a antibody, prdm1.S antibody, prdm1 antibody, Prdm1 antibody
- Background
- Blimp-1 (B lymphocyte-induced maturation protein) is a nuclear zinc-finger containing transcriptional repressor and plays an important role in terminal B-cell development. Expression of Blimp-1 is sufficient to drive terminal differentiation of BCL1 lymphoma cells into antibody secreting plasma cells, increasing the expression of the cell surface marker Syndecan-1. In addition, Blimp-1 has been found during macrophage differentiation and in a subset of T-cells, which suggests that it may play a wider role in homeostasis and differentiation.
- UniProt
- O75626
- Pathways
- Regulation of Muscle Cell Differentiation
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