HMGN1 antibody (pSer21, pSer25) (FITC)

Catalog No. ABIN801280

This Rabbit Polyclonal antibody specifically detects HMGN1 in WB, IF (p) and IF (cc). It exhibits reactivity toward Human.

Quick Overview for HMGN1 antibody (pSer21, pSer25) (FITC) (ABIN801280)

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This HMGN1 antibody is conjugated to FITC

Application: Western Blotting (WB), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunofluorescence (Cultured Cells) (IF (cc))

Product Details anti-HMGN1 Antibody (FITC)

Binding Specificity: pSer21, pSer25

Predicted Reactivity: Human,Mouse,Rat,Dog,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic phosphopeptide derived from human HMGN1 around the phosphorylation site of Ser20+Ser24

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for HMGN1

Target: HMGN1 (High Mobility Group Nucleosome Binding Domain 1 (HMGN1))

Alternative Name: HMGN1+

Background:

Synonyms: HMG14 phospho S21 + S25, High mobility group nonhistone chromosomal protein 14, High mobility group nucleosome binding 1, High mobility group nucleosome binding domain containing protein 1, High mobility group protein 14, High-mobility group nucleosome binding domain 1, HMG14, HMGN 1, HMGN1, MGC104230, MGC117425, Nonhistone chromosomal protein HMG-14, Nonhistone chromosomal protein HMG14, FLJ27265, FLJ31471.

Background: Chromosomal protein HMG14 binds to the inner side of the nucleosomal DNA, thus altering the interaction between the DNA and the histone octamer and is involved in the process that maintains transcribable genes in an appropriate chromatin conformation. HMG14 has been implicated as a contributing factor in the etiology of Down syndrome.

Gene ID: 3150

Pathways: Chromatin Binding