TP53I3 antibody

Catalog No. ABIN2734080

This Mouse Monoclonal antibody specifically detects TP53I3 in WB. It exhibits reactivity toward Human.

Quick Overview for TP53I3 antibody (ABIN2734080)

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TP53I3 antibody is un-conjugated

Application: Western Blotting (WB)

Clone: 3E3

Product Details anti-TP53I3 Antibody

Characteristics: Homo sapiens tumor protein p53 inducible protein 3 (TP53I3), transcript variant 2

Purification: Purified from mouse ascites fluids by affinity chromatography

Immunogen: Full length human recombinant protein of human TP53I3(NP_671713) produced in HEK293T cell.

Isotype: IgG1

Application Details

Application Notes: WB 1:2000,

Comment:

The concentration of the product may vary between diferrent lots.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5-1.0 mg/mL

Buffer: PBS (PH 7.3) containing 1 % BSA, 50 % glycerol and 0.02 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Target Details for TP53I3

Target: TP53I3 (Tumor Protein P53 Inducible Protein 3 (TP53I3))

Alternative Name: TP53I3

Background: The protein encoded by this gene is similar to oxidoreductases, which are enzymes involved in cellular responses to oxidative stresses and irradiation. This gene is induced by the tumor suppressor p53 and is thought to be involved in p53-mediated cell death. It contains a p53 consensus binding site in its promoter region and a downstream pentanucleotide microsatellite sequence. P53 has been shown to transcriptionally activate this gene by interacting with the downstream pentanucleotide microsatellite sequence. The microsatellite is polymorphic, with a varying number of pentanucleotide repeats directly correlated with the extent of transcriptional activation by p53. It has been suggested that the microsatellite polymorphism may be associated with differential susceptibility to cancer. At least two transcript variants encoding the same protein have been found for this gene.

Molecular Weight: 35.4 kDa

Gene ID: 9540

NCBI Accession: NM_147184

HGNC: 9540

Pathways: p53 Signaling