Aurora A antibody

Catalog No. ABIN865470

The Mouse Monoclonal anti-Aurora A antibody (Clone 4G10) (ABIN865470) specifically detects Aurora A in WB, ELISA and IHC. The antibody is reactive with Human, Rat and Monkey samples.

Quick Overview for Aurora A antibody (ABIN865470)

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Reactivity: Human, Rat, Monkey

Host: Mouse

Clonality: Monoclonal

Conjugate: This Aurora A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (IHC)

Clone: 4G10

Product Details anti-Aurora A Antibody

Purification: Ascitic fluid

Immunogen: Purified recombinant fragment of human AURKA expressed in E. Coli.

Isotype: IgG1

Application Details

Application Notes: WB: 1/500 - 1/2000, IHC: 1/200-1/1000, ELISA: Propose dilution 1/10000.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 100g/100l

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for Aurora A

Target: Aurora A (AURKA) (Aurora Kinase A (AURKA))

Alternative Name: AURKA

Background: Aurora A plays a role in cell cycle regulation during anaphase and/or telophase, in relation to the function of the centrosome/spindle pole region during chromosome segregation. Aurora A plays a key role during tumor development and progression and is overexpressed in many human cancers including breast, ovarian and colorectal. Aurora A is viewed as a potential target for anticancer drug treatment. Tissue specificity: Highly expressed in testis and weakly in skeletal muscle, thymus and spleen. Also highly expressed in colon, ovarian, prostate, neuroblastoma, breast and cervical cancer cell lines. Synonyms: AIK, ARK1, AURA, BTAK, STK6, STK7, STK15, AURORA2, MGC34538, AURKA

Molecular Weight: 48kDa

Gene ID: 6790

Pathways: Cell Division Cycle, Asymmetric Protein Localization