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OCT4 antibody
POU5F1
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-OCT4 Antibody
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Target
See all OCT4 (POU5F1) Antibodies
OCT4 (POU5F1)
(POU Class 5 Homeobox 1 (POU5F1))
Reactivity
All reactivities for OCT4 antibodies
Human
Host
All hosts for OCT4 antibodies
Rabbit
Clonality
All clonalities for OCT4 antibodies
Polyclonal
Conjugate
All conjugates for OCT4 antibodies
This OCT4 antibody is un-conjugated
Application
All applications for OCT4 antibodies
Western Blotting (WB)
Specificity
This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of OCT4.
Cross-Reactivity
Human, Mouse (Murine)
Characteristics
Positive control: NCCIT, F9. Cellular Localization: Cell nucleus
Purification
Immunogen affinity purified
Isotype
IgG
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Alternatives
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Application Details
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Application Notes
WB: 1:1,000
Restrictions
For Research Use only
Handling
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Format
Liquid
Buffer
1xTBS (pH7.4), 0.5% BSA, 40% Glycerol
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C
Target Details for OCT4
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Target
OCT4 (POU5F1)
(POU Class 5 Homeobox 1 (POU5F1))
Alternative Name
OCT-4 (POU5F1 Products )
Synonyms
OCT3 antibody, OCT4 antibody, OTF-3 antibody, OTF3 antibody, OTF4 antibody, Oct-3 antibody, Oct-4 antibody, POU5F1 antibody, gp9 antibody, gp-9 antibody, oct4 antibody, pou2 antibody, POU-2 antibody, cb197 antibody, spg/pou2 antibody, chunp6868 antibody, wu:fd18d06 antibody, NF-A3 antibody, Oct-3/4 antibody, Oct3 antibody, Oct3/4 antibody, Oct4 antibody, Otf-3 antibody, Otf-4 antibody, Otf3 antibody, Otf3-rs7 antibody, Otf3g antibody, Otf4 antibody, POU class 5 homeobox 1 antibody, POU domain, class 5, transcription factor 3 antibody, POU domain, class 5, transcription factor 1 antibody, POU5F1 antibody, pou5f3 antibody, Pou5f1 antibody
Background
Oct-4 (POU5F1) is a transcription factor expressed in the totipotent and pluripotent stem cells of the pregastrulation embryo. It is also expressed in primordial germ cells and in the female germ li line. OCT4 binds to the octamer motif (5'-ATTTGCAT-3') and forms a trimeric complex with SOX2 on DNA and controls the expression of a number of genes involved in embryonic development such as YES1, FGF4, UTF1 and ZFP206. It is critical for early embryogenesis and for embryonic stem cell pluripotency.
Molecular Weight
45kDa
UniProt
P20263
Pathways
Stem Cell Maintenance
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