LGR5 antibody

Catalog No. ABIN866063

Product Details anti-LGR5 Antibody

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LGR5 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Specificity: This antibody is produced by immunizing rabbits with a synthetic peptide (KLH-coupled) corresponding to a region of LGR5.

Cross-Reactivity: Human, Mouse (Murine)

Characteristics: Positive control: F9, NCCIT Q9Z1P4(mouse). Cellular Localization: Cell membrane Cell nucleus

Purification: Immunogen affinity purified

Isotype: IgG

Application Details

Application Notes: WB: 1:1,000-1:2,000. ICC: 1:50

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1xTBS (pH7.4), 0.5% BSA, 40% Glycerol

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for LGR5

Target: LGR5 (Leucine-Rich Repeat Containing G Protein-Coupled Receptor 5 (LGR5))

Alternative Name: LGR5 (LGR5 Products)

Synonyms: lgr5-a antibody, lgr5a antibody, FEX antibody, Gpr49 antibody, GPR49 antibody, GPR67 antibody, GRP49 antibody, HG38 antibody, leucine-rich repeat containing G protein-coupled receptor 5 L homeolog antibody, leucine rich repeat containing G protein coupled receptor 5 antibody, leucine rich repeat containing G protein-coupled receptor 5 antibody, lgr5.L antibody, Lgr5 antibody, LGR5 antibody

Background: G-protein coupled receptor GPR49 (also known as Leucine-rich repeat-containing G-protein coupled receptor 5, Lgr5) is a stem cell marker of the intestinal epithelium and the hair follicule. It is expressed in the gonads, the adrenal gland, and in the brain, overexpressed in cancers of the ovary, colon and liver.

Molecular Weight: 95kDa

UniProt: O75473

Pathways: WNT Signaling