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GFAP antibody (Glial Fibrillary Acidic Protein) (AA 423-427)

Details for Product anti-GFAP Antibody No. ABIN871512, Supplier: Log in to see
Antigen
  • GFAP
  • AI836096
  • cb345
  • etID36982.3
  • gfapl
  • wu:fb34h11
  • wu:fk42c12
  • xx:af506734
  • zgc:110485
  • glial fibrillary acidic protein
  • GFAP
  • LOC100136168
  • gfap
  • Gfap
Epitope
AA 423-427
70
69
33
29
24
14
13
6
6
6
5
4
4
3
3
3
3
3
3
3
3
2
2
2
2
2
2
2
2
2
1
1
1
1
1
1
1
Reactivity
Human, Rat (Rattus)
698
309
294
179
176
121
86
27
27
22
21
21
17
16
7
5
5
5
3
3
2
2
1
1
1
1
1
1
Host
Rabbit
452
310
27
26
4
3
2
Clonality
Polyclonal
Conjugate
This GFAP antibody is un-conjugated
33
24
24
17
11
11
9
8
8
7
5
5
5
5
5
5
5
5
4
4
4
4
4
4
4
4
4
4
4
4
3
3
3
3
3
3
2
2
1
1
Application
Western Blotting (WB)
588
321
263
255
236
232
138
83
71
33
16
12
11
10
8
8
7
6
6
5
4
3
1
1
1
1
1
1
1
Options
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Immunogen Peptide sequence around AA 423-427 (E-S-K-Q-E) derived from Human GFAP. Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
Specificity The antibody detects endogenous level of total GFAP protein.
Purification Affinity purified
Alternative Name GFAP (GFAP Antibody Abstract)
Background GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
Molecular Weight 50 kDa
Gene ID 2670
NCBI Accession NP_002046
UniProt P14136
Research Area Stem Cells, Cytoskeleton, Glia marker, Cell/Tissue Markers, Neurology
Application Notes Western blotting: 1:500-1:1000
Immunofluorescence: 1:100-1:200
Restrictions For Research Use only
Format Liquid
Concentration 1 mg/mL
Buffer Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative Sodium azide
Precaution of Use This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage 4 °C/-20 °C
Storage Comment Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Background publications Nielsen, Holm, Johansen, Bonven, Jørgensen, Jørgensen: "A new splice variant of glial fibrillary acidic protein, GFAP epsilon, interacts with the presenilin proteins." in: The Journal of biological chemistry, Vol. 277, Issue 33, pp. 29983-91, 2002 (PubMed).

Bongcam-Rudloff, Nistér, Betsholtz, Wang, Stenman, Huebner, Croce, Westermark: "Human glial fibrillary acidic protein: complementary DNA cloning, chromosome localization, and messenger RNA expression in human glioma cell lines of various phenotypes." in: Cancer research, Vol. 51, Issue 5, pp. 1553-60, 1991 (PubMed).