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CCR5 antibody (AA 11-15)
CCR5
Reactivity: Human
WB
Host: Rabbit
Polyclonal
unconjugated
Product Details anti-CCR5 Antibody
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Target
See all CCR5 Antibodies
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Binding Specificity
All epitopes for CCR5 antibodies
AA 11-15
Reactivity
All reactivities for CCR5 antibodies
Human
Host
All hosts for CCR5 antibodies
Rabbit
Clonality
All clonalities for CCR5 antibodies
Polyclonal
Conjugate
All conjugates for CCR5 antibodies
This CCR5 antibody is un-conjugated
Application
All applications for CCR5 antibodies
Western Blotting (WB)
Specificity
The antibody detects endogenous level of total CCR5 (CD195) protein.
Purification
Affinity purified
Immunogen
Peptide sequence around AA 11-15 (D-I-N-Y-Y) derived from Human CCR5 (CD195) . Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjugates.
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Alternatives
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Application Details
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Application Notes
Western blotting: 1:500-1:1000
Restrictions
For Research Use only
Handling
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Format
Liquid
Concentration
1 mg/mL
Buffer
Phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150 mM NaCl, 0.02 % sodium azide and 50 % glycerol.
Preservative
Sodium azide
Precaution of Use
This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
Storage
4 °C/-20 °C
Storage Comment
Store at -20 °C for long term preservation (recommended). Store at 4 °C for short term use.
Target Details for CCR5
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Target
CCR5
(Chemokine (C-C Motif) Receptor 5 (CCR5))
Alternative Name
CCR5 (CD195) (CCR5 Products )
Synonyms
CC-CKR-5 antibody, CCCKR5 antibody, CCR-5 antibody, CD195 antibody, CKR-5 antibody, CKR5 antibody, CMKBR5 antibody, IDDM22 antibody, Ckr5 antibody, Cmkbr5 antibody, CCR1-L antibody, GPCR antibody, CCR5 antibody, AM4-7 antibody, C-C motif chemokine receptor 5 (gene/pseudogene) antibody, chemokine (C-C motif) receptor 5 antibody, C-C motif chemokine receptor 5 antibody, CCR5 antibody, Ccr5 antibody
Background
Receptor for a number of inflammatory CC-chemokines including MIP-1-a, MIP-1-beta and RANTES and subsequently transduces a signal by increasing the intracellular calcium ion level. May play a role in the control of granulocytic lineage proliferation or differentiation. Acts as a coreceptor (CD4 being the primary receptor) for HIV-1 R5 isolates.
Molecular Weight
41 kDa
Gene ID
1234
NCBI Accession
NP_000570
UniProt
P51681
Pathways
Cellular Response to Molecule of Bacterial Origin , cAMP Metabolic Process , Regulation of Cell Size
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