CLASP2 antibody (Cytoplasmic Linker Associated Protein 2) (Alexa Fluor 350)

Details for Product anti-CLASP2 Antibody No. ABIN891141, Supplier: Log in to see
Antigen
  • zgc:77279
  • DKFZp459M112
  • 1500004F14Rik
  • 8030404L10Rik
  • C77448
  • CLASP2beta
  • mKIAA0627
  • cytoplasmic linker associated protein 2
  • CLIP associating protein 2
  • clasp2
  • CLASP2
  • Clasp2
Alternatives
anti-Human CLASP2 antibody for Enzyme Immunoassay
Reactivity
Human, Mouse (Murine), Rat (Rattus)
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Host
Rabbit
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10
2
Clonality
Polyclonal
Conjugate
This CLASP2 antibody is conjugated to Alexa Fluor 350
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2
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1
Application
Immunofluorescence (Paraffin-embedded Sections) (IF (p))
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Options
Supplier
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Immunogen KLH conjugated synthetic peptide derived from human CLASP2
Isotype IgG
Purification Purified by Protein A.
Alternative Name Clasp2 (CLASP2 Antibody Abstract)
Background

CLASP2 is a microtubule plus end tracking protein that promotes the stabilization of dynamic microtubules and is required for the polarization of the cytoplasmic microtubule arrays in migrating cells towards the leading edge of the cell. CLASP2 may act at the cell cortex to enhance the frequency of rescue of depolymerizing microtubules by attaching their plus ends to cortical platforms composed of ERC1 and PHLDB2. This cortical microtubule stabilizing activity is regulated at least in part by phosphatidylinositol 3 kinase signaling. CLASP2 also performs a similar stabilizing function at the kinetochore which is essential for the bipolar alignment of chromosomes on the mitotic spindle.

Synonyms: CLASP 2, CLIP associating protein 2, Cytoplasmic linker associated protein 2, hOrbit2, KIAA0627, Multiple asters Mast like homolog 2, Protein Orbit homolog 2, CLAP2_HUMAN.

Gene ID 23122
Pathways Microtubule Dynamics, Maintenance of Protein Location
Application Notes IF(IHC-P) 1:50-200
Restrictions For Research Use only
Format Liquid
Concentration 1 μg/μL
Buffer Aqueous buffered solution containing 1 % BSA, 50 % glycerol and 0.09 % sodium azide.
Preservative Sodium azide
Precaution of Use This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
Storage 4 °C
Storage Comment Store at 4°C
Expiry Date 12 months
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