NAIP antibody (AA 1151-1250) (Alexa Fluor 647)

Catalog No. ABIN907599

Product Details anti-NAIP Antibody (Alexa Fluor 647)

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Binding Specificity: AA 1151-1250

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NAIP antibody is conjugated to Alexa Fluor 647

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human NAIP

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NAIP

Target: NAIP (NLR Family, Apoptosis Inhibitory Protein (NAIP))

Alternative Name: NAIP (NAIP Products)

Synonyms: BIRC1 antibody, NLRB1 antibody, psiNAIP antibody, AV364616 antibody, Birc1a antibody, D13Lsd1 antibody, Naip antibody, Naip-rs1 antibody, NLR family apoptosis inhibitory protein antibody, NLR family, apoptosis inhibitory protein 1 antibody, NAIP antibody, Naip1 antibody

Background:

Synonyms: Baculoviral IAP repeat containing 1, Baculoviral IAP repeat-containing protein 1, BIRC 1, BIRC1, BIRC1_HUMAN, Birc1a, NAIP, Naip1, Neuronal apoptosis inhibitory protein, NLR family apoptosis inhibitory protein, NLR family BIR domain containing 1, NLRB 1, NLRB1, Nucleotide binding oligomerization domain leucine rich repeat and BIR domain containing 1, Psi neuronal apoptosis inhibitory protein, psiNAIP, Similar to occludin.

Background: Prevents motor-neuron apoptosis induced by a variety of signals. Possible role in the prevention of spinal muscular atrophy that seems to be caused by inappropriate persistence of motor-neuron apoptosis: mutated or deleted forms of NAIP have been found in individuals with severe spinal muscular atrophy.

Gene ID: 4671

Pathways: Apoptosis, Inflammasome