PROCR antibody

Catalog No. ABIN920711

Product Details anti-PROCR Antibody

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Reactivity: Human

Host: Rat

Clonality: Monoclonal

Conjugate: This PROCR antibody is un-conjugated

Application: Immunohistochemistry (IHC), Flow Cytometry (FACS)

Specificity: The rat monoclonal antibody LMR-42 detects an outer-surface epitope of a 55 kDa plasma membrane protein over-expressed in several human non-Pgp multidrug-resistant (MDR) tumor cell lines. LMR-42 has potential value for the detection of EPCR, which may mediate anti-coagulant and anti-inflammatory functions along vascular endothelia. Whether and how anti-coagulant and anti-inflammatory functions of EPCR facilitate oncogenesis and/or drug-resistance is unclear.

Immunogen: Expression cloning revealed that the LMR-42 antigen is identical to the human endothelial cell protein C receptor (EPCR). Protein C is the zymogen of the key anticoagulant enzyme, activated protein C (APC).

Clone: LMR-42

Isotype: IgG2b

Application Details

Application Notes: Immunohistochemistry: Use at a 1:20 dilution on frozen sections, air-dried or acetone fixed cells. Flow cytometry: No cell permeabilization required.

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: 1 mL antibody (>200 tests) at 100 µg IgG/mL in serum-free culture supernatant with protein stabilizer and 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Target Details for PROCR

Target: PROCR (Protein C Receptor, Endothelial (PROCR))

Alternative Name: Endothelial Cell Protein C Receptor (PROCR Products)

Synonyms: PROCR antibody, CCCA antibody, CCD41 antibody, EPCR antibody, AI325044 antibody, Ccca antibody, Ccd41 antibody, Epcr antibody, protein C receptor antibody, protein C receptor, endothelial antibody, PROCR antibody, Procr antibody