PFKM antibody (C-Term)

Catalog No. ABIN926683

This Rabbit Polyclonal antibody specifically detects PFKM in WB. It exhibits reactivity toward Human.

Quick Overview for PFKM antibody (C-Term) (ABIN926683)

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PFKM antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-PFKM Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: PFKM antibody was raised in rabbit using the C terminal of PFKM as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

PFKM Blocking Peptide, (ABIN5615327), is also available for use as a blocking control in assays to test for specificity of this PFKM antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for PFKM

Target: PFKM (phosphofructokinase, Muscle (PFKM))

Alternative Name: PFKM

Background: Three phosphofructokinase isozymes exist in humans: muscle, liver and platelet. These isozymes function as subunits of the mammalian tetramer phosphofructokinase, which catalyzes the phosphorylation of fructose-6-phosphate to fructose-1,6-bisphosphate. Tetramer composition varies depending on tissue type. This gene encodes the muscle-type isozyme. Mutations in this gene have been associated with glycogen storage disease type VII, also known as Tarui disease. Alternatively spliced transcript variants have been described. Synonyms: Polyclonal PFKM antibody, Anti-PFKM antibody, phosphofructokinase, muscle antibody, GSD7 antibody, MGC8699 antibody, PFK-1 antibody, PFK1 antibody, PFKA antibody, PFKX antibody.

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Carbohydrate Homeostasis, Warburg Effect