OGG1 antibody (C-Term)

Catalog No. ABIN926698

This Rabbit Polyclonal antibody specifically detects OGG1 in WB. It exhibits reactivity toward Human.

Quick Overview for OGG1 antibody (C-Term) (ABIN926698)

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This OGG1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-OGG1 Antibody

Binding Specificity: C-Term

Purification: Purified

Immunogen: OGG1 antibody was raised in rabbit using the C terminal of OGG1 as the immunogen

Application Details

Application Notes: Optimal conditions should be determined by the investigator.

Comment:

OGG1 Blocking Peptide, (ABIN936997), is also available for use as a blocking control in assays to test for specificity of this OGG1 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for OGG1

Target: OGG1 (8-Oxoguanine DNA Glycosylase (OGG1))

Alternative Name: OGG1

Background: This gene encodes the enzyme responsible for the excision of 8-oxoguanine, a mutagenic base byproduct which occurs as a result of exposure to reactive oxygen. The action of this enzyme includes lyase activity for chain cleavage. Alternative splicing of the C-terminal region of this gene classifies splice variants into two major groups, type 1 and type 2, depending on the last exon of the sequence. Type 1 alternative splice variants end with exon 7 and type 2 end with exon 8. All variants share the N-terminal region in common, which contains a mitochondrial targeting signal that is essential for mitochondrial localization. Synonyms: Polyclonal OGG1 antibody, Anti-OGG1 antibody, 8-oxoguanine DNA glycosylase antibody, HMMH antibody, HOGG1 antibody, MUTM antibody, OGH1 antibody.

Pathways: DNA Damage Repair