CHRNB3 antibody (Middle Region)
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- Target See all CHRNB3 Antibodies
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
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Binding Specificity
- Middle Region
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Reactivity
- Human, Mouse, Rat, Dog, Chicken, Xenopus laevis
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This CHRNB3 antibody is un-conjugated
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Application
- Western Blotting (WB)
- Cross-Reactivity
- Mouse (Murine), Rat (Rattus), Dog (Canine), Chicken, Frog
- Purification
- Purified
- Immunogen
- CHRNB3 antibody was raised in rabbit using the middle region of CHRNB3 as the immunogen
- Top Product
- Discover our top product CHRNB3 Primary Antibody
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- Application Notes
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WB: 0.03 µg/mL
Optimal conditions should be determined by the investigator. - Comment
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CHRNB3 Blocking Peptide, catalog no. 33R-10069, is also available for use as a blocking control in assays to test for specificity of this CHRNB3 antibody
- Restrictions
- For Research Use only
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- Format
- Lyophilized
- Concentration
- Lot specific
- Buffer
- Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.
- Handling Advice
- Avoid repeated freeze/thaw cycles.
- Storage
- 4 °C/-20 °C
- Storage Comment
- Store at 4 °C, following reconstitution, aliquot and store at -20 °C.
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- Target
- CHRNB3 (Cholinergic Receptor, Nicotinic, beta 3 (Neuronal) (CHRNB3))
- Alternative Name
- CHRNB3 (CHRNB3 Products)
- Synonyms
- 5730417K16Rik antibody, Acrb3 antibody, NACHR antibody, CHRNB3 antibody, chrnb3 antibody, cholinergic receptor nicotinic beta 3 subunit antibody, neuronal acetylcholine receptor subunit beta-3 antibody, cholinergic receptor, nicotinic, beta polypeptide 3 antibody, cholinergic receptor, nicotinic beta 3 L homeolog antibody, cholinergic receptor, nicotinic beta 3 antibody, cholinergic receptor, nicotinic, beta 3b (neuronal) antibody, cholinergic receptor, nicotinic, beta polypeptide 3a antibody, CHRNB3 antibody, CpipJ_CPIJ012638 antibody, Chrnb3 antibody, chrnb3.L antibody, chrnb3 antibody, chrnb3b antibody, chrnb3a antibody
- Background
- Nicotinic acetylcholine receptors (nAChRs) are ligand-gated ion channels nAChRs are pentameric structures that are made up of combinations of individual subunits. CHRNB3 is one of the subunits of nAChR. Twelve neuronal nAChR subunits have been described, alpha2-alpha10 and beta2-beta4. CHRNB3 decreased the channel mean open time and burst length. There was also an increase in single channel slope conductance. On the other hand, the calcium permeability and the pharmacological properties of beta3-containing receptors differed little from those of without beta3. Dysfunction of nAChR has been linked to a number of human diseases such as schizophrenia, Alzheimer's and Parkinson's diseases. nAChRs also play a significant role in nicotine addiction. Synonyms: Polyclonal CHRNB3 antibody, Anti-CHRNB3 antibody, cholinergic receptor, nicotinic, beta 3 antibody.
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