ATP6V1G2 antibody (Middle Region)

Catalog No. ABIN928986

Product Details anti-ATP6V1G2 Antibody

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Binding Specificity: Middle Region

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ATP6V1G2 antibody is un-conjugated

Application: Western Blotting (WB)

Purification: Purified

Immunogen: ATP6 V6 2 antibody was raised in rabbit using the middle region of ATP6 6 2 as the immunogen

Application Details

Application Notes: WB: 0.2-1 µg/mL
Optimal conditions should be determined by the investigator.

Comment:

ATP6V1G2 Blocking Peptide, catalog no. 33R-6773, is also available for use as a blocking control in assays to test for specificity of this ATP6V1G2 antibody

Restrictions: For Research Use only

Handling

Format: Lyophilized

Concentration: Lot specific

Buffer: Lyophilized powder. Add 50 µL of distilled water. Final antibody concentration is 1 mg/mL in PBS buffer.

Handling Advice: Avoid repeated freeze/thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Store at 4 °C, following reconstitution, aliquot and store at -20 °C.

Target Details for ATP6V1G2

Target: ATP6V1G2 (ATPase, H+ Transporting, Lysosomal 13kDa, V1 Subunit G2 (ATP6V1G2))

Alternative Name: ATP6V1G2 (ATP6V1G2 Products)

Synonyms: ATP6G antibody, ATP6V1G1 antibody, ATP6G2 antibody, NG38 antibody, VMA10 antibody, ATP6G1 antibody, 1500002D01Rik antibody, Atp6g2 antibody, VAG2 antibody, ATPase H+ transporting V1 subunit G2 antibody, ATPase, H+ transporting, lysosomal V1 subunit G2 antibody, ATP6V1G2 antibody, Atp6v1g2 antibody

Background: This gene encodes a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of intracellular compartments of eukaryotic cells. V-ATPase dependent acidification is necessary for such intracellular processes as protein sorting, zymogen activation, receptor-mediated endocytosis, and synaptic vesicle proton gradient generation. V-ATPase is composed of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of three A and three B subunits, two G subunits plus the C, D, E, F, and H subunits. The V1 domain contains the ATP catalytic site. The V0 domain consists of five different subunits: a, c, c', c'', and d. Additional isoforms of many of the V1 and V0 subunit proteins are encoded by multiple genes or alternatively spliced transcript variants. This encoded protein is one of three V1 domain G subunit proteins. Synonyms: Polyclonal ATP6V1G2 antibody, Anti-ATP6V1G2 antibody, ATPase, H+ transporting, lysosomal 13kDa, V1 subunit G2 antibody, ATP6G antibody, ATP6G2 antibody, NG38 antibody, VMA10 antibody.

Pathways: Transition Metal Ion Homeostasis, Proton Transport